Results 101 to 110 of about 6,176 (169)

Development of new methods for the synthesis of pyrazoles, 4-iodopyrazoles, isoxazoles and 1,2,4-oxadiazoles

, 2011
Synthesis of five-membered heteroaromatic compounds such as pyrazoles, isoxazoles and 1,2,4-oxadiazoles are important for pharmaceutical industry and material science due to their applications.
ARİF KIVRAK
core  

Enhanced antipyretic activity of new 2, 5-substituted 1, 3, 4-oxadiazoles encapsulated in alginate/gelatin particulated systems

, 2012
cited By 4International audienceNew 1,3,4-oxadiazoles with pharmacological potential, derived from 5-nitroindazole, have been synthesized. Their chemical structure has been established by elemental and spectral analyses (FT-IR and 1H-NMR).
Holban, M., Cheptea, C., Desbrieres, Jacques, Lionte, C., Şunel, V., Popa, M.   +5 more
core   +1 more source

Synthesis of novel 1,2,4-oxadiazole-isoxazoline hybrids and their in silico potential with adenosine receptors. [PDF]

Beilstein J Org Chem
Mohammed PS, Dalo MKS, Yazıcı OC, Yildirim M, Sağırlı A.   +4 more
europepmc   +1 more source

Iodine-mediated 2,5-di(aryl/heteroaryl)-1,3,4-oxadiazoles: synthesis, and <i>in vitro</i> and <i>in silico</i> studies of anticancer and antifungal properties. [PDF]

RSC Adv
Ramesha T, Shenoy TN, Subba Reddy UV, Ega JK, Gogula SS, Swathi B, Burgula S, Reddy PM, Abdul Salam AA.   +8 more
europepmc   +1 more source

Molecular Docking and In Vitro Studies of Synthesized Oxadiazole Derivatives as Urease Inhibitors

Journal of Mathematical and Fundamental Sciences
A novel sequence of 1,3,4-oxadiazoles (7a–h) was synthesized. The compounds were characterized by IR, ¹H NMR, and MS analyses. They were also examined to determine whether they could prevent urease from functioning.
Kamran Mehdi, Obaid-ur-Rahman Abid, Saqib Khan, Is Helianti, Muhammad Ikhlas Abdjan, Aleesha Aleesha, Muhammad Ali, Naseer Ahmed   +7 more
doaj  

Mechanism-based inhibition of zinc-dependent histone deacetylases. [PDF]

RSC Chem Biol
Christianson DW.
europepmc   +1 more source

Design, synthesis, and enzyme kinetic evaluation of oxadiazole derivatives as nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors: an integrated <i>in vitro</i> and <i>in silico</i> approach. [PDF]

RSC Adv
Abbas SZ, Ashraf Z, Roshan S, Sughra K, Rahat MA, Shakir I, Latif M.   +6 more
europepmc   +1 more source

Activity Profiling of Nitro-Substituted Di(Hetero)Aryl 1,3,4- and 1,2,4-Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential. [PDF]

Arch Pharm (Weinheim)
Šikorová E, Štěpánková Š, Frýbová E, Konečná K, Korbielová J, Švarcová M, Janďourek O, Pflégr V, Bősze S, Krátký M.   +9 more
europepmc   +1 more source

Chemo- and Regioselective Synthesis of 3,4-Dihydropyrimidin-4-ones from 4,5-Dihydro-1,2,4-oxadiazoles and Chromium Alkoxy Alkynyl Fischer Carbene Complexes. [PDF]

Org Lett
Sánchez-Alonso S, Menéndez MI, Merino I, Aguilar E.   +3 more
europepmc   +1 more source

Benzo[<i>d</i>]imidazole anchored oxadiazole derivatives: synthesis, characterization, biological evaluation, <i>in silico</i> docking and ADME-T analysis. [PDF]

RSC Adv
Salluri YR, Chepuri K, Anwar S.
europepmc   +1 more source