Results 81 to 90 of about 5,960 (212)
ChemistryOpen, 2020 1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola +2 more
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Antibacterial Activity, Structure-Activity Relationships, and Scale-Up Reaction of 1,3,4-Oxadiazoles [PDF]
, 2022 Oxadiazoles are compounds in the field of organic chemistry that have been gathering interest in the medicinal chemistry and microbiology communities for their biological properties, which range from anti-inflammatory agents, to chemotherapy drugs, to ...
Smith, Olivia Marie
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Synthesis of Oxadiazole Derivatives from Terephthalic Acid
Chemistry ProceedingsOxadiazoles, nitrogen-containing heterocycles, are attracting interest due to their promising biological activities. This study focuses on the synthesis of oxadiazole derivatives from functionalized intermediates derived from terephthalic acid, a ...
Fekih Yasmine +2 more
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Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles
, 2016 We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SNAr substitution using phosphonium reagents (e.g., BOP).
Zhao-Kui Wan (2004907) +1 more
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, 2017 Background and Objectives: 1,2,4-Oxadiazoles show a high reactivity and represent starting compounds for the synthesis of several other heterocycles. Some their derivatives can give the so called Boulton-Katritzky Reactions (BKR) which opens the way to ...
Zuppiroli, Luca +17 more
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Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles bearing an indole ring [PDF]
, 2019 1,3,4-oxadiazoles have been widely studied by many researchers in various fields. Due to its heterocyclic structure, 1,3,4-oxadiazoles possess of many biological and pharmacological activities such as antibacterial, anticancer, antiinflammatory ...
Kong, Kian Liang
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Molecules, 2011 A series of 5-substituted-4-amino-1,2,4-triazole-3-thioesters was synthesized by converting variously substituted organic acids successively into the corresponding esters, hydrazides, 5-substituted-1,3,4-oxadiazole-2-thiols, 5-substituted-1,2,4-triazole ...
Aurangzeb Hasan +2 more
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Oxadiazoles as potential drugs III.
, 2019 Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Title of diploma thesis: Oxadiazoles as potential drugs III. Student: Michaela Lukáčová Supervisor: PharmDr. Marta Kučerová, Ph.D.
Lukáčová, Michaela
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ChemMedChemAbstractTuberculosis remains a leading global health threat, exacerbated by the emergence of multi‐drug‐resistant strains. The search for novel therapeutic agents is critical in addressing this challenge. This review systematically summarizes the potential of oxadiazole derivatives as promising candidates in antimycobacterial drug discovery.
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MoleculesAn unparalleled copper(I)-catalyzed synthesis of 1,3,4-oxadiazoles from tertiary amines in one step has been described. The one-pot reactions involving (N-isocyanimine)triphenylphosphorane, tertiary amines, and carboxylic acids resulted in the formation ...
Mei Sun +10 more
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