Results 81 to 90 of about 6,176 (169)
Synthesis of Oxadiazole Derivatives from Terephthalic Acid
Chemistry ProceedingsOxadiazoles, nitrogen-containing heterocycles, are attracting interest due to their promising biological activities. This study focuses on the synthesis of oxadiazole derivatives from functionalized intermediates derived from terephthalic acid, a ...
Fekih Yasmine +2 more
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Oxadiazoles as potential drugs III.
, 2019 Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Title of diploma thesis: Oxadiazoles as potential drugs III. Student: Michaela Lukáčová Supervisor: PharmDr. Marta Kučerová, Ph.D.
Lukáčová, Michaela
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Nickel-Catalyzed C−H Alkenylation and Alkylation of 1,3,4-Oxadiazoles with Alkynes and Styrenes
, 2016 The addition reaction of 1,3,4-oxadiazoles to alkynes via C−H bond cleavage efficiently proceeds in the presence of a nickel catalyst. This direct coupling allows a facile access to alkenyl-substituted oxadiazoles.
Tomoya Mukai (2311078) +3 more
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Stereoselective synthesis, synthetic and pharmacological application of monoterpene-based 1,2,4- and 1,3,4-oxadiazoles [PDF]
, 2017 Stereoselective synthesis of monoterpene-based 1,2,4- and 1,3,4-oxadiazole derivatives was accomplished starting from α,β-unsaturated carboxylic acids, obtained by the oxidation of (−)-2-carene-3-aldehyde and commercially available (−)-myrtenal.
Bérdi Péter +9 more
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Molecules, 2011 A series of 5-substituted-4-amino-1,2,4-triazole-3-thioesters was synthesized by converting variously substituted organic acids successively into the corresponding esters, hydrazides, 5-substituted-1,3,4-oxadiazole-2-thiols, 5-substituted-1,2,4-triazole ...
Aurangzeb Hasan +2 more
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ChemistryOpen, 2019 We demonstrate modular modifications of the widely employed emitter 2,4,5,6‐tetra(9H‐carbazol‐9‐yl)isophthalonitrile (4CzIPN) by replacing one or both nitrile acceptors with oxadiazole groups via a tetrazole intermediate.
Fabian Hundemer +7 more
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Tandem Reactions of 1,2,4-Oxadiazoles with Allylamines
, 2016 A reaction of 3-chloro-1,2,4-oxadiazoles with allylamine and diallylamine has been investigated. 3,3a,4,5-Tetrahydroisoxazolo[3,4-d]pyrimidines are produced through a tandem ANRORC/[3 + 2]cycloaddition pathway consisting of the addition of allylamine to ...
Antonio Palumbo Piccionello (564720) +2 more
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, 2008 The uses of 1,2,4-oxadiazoles include those as agonists at muscarinic receptors, 5-hydroxytryptamine (5-HT) receptor antagonists, benzodiazepine receptor agonists, potent antagonists of the (serotonin) 5-HT1B/D receptors, muscarinic receptor ...
K. Hemming, Hemming, Karl, Hemming, K.
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Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles
Anais da Academia Brasileira de Ciências, 2015 An altered form of the cellular prion protein, the PrPScor PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies.
CLAUDIA P. FIGUEIREDO +10 more
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Synthesis and Antibacterial Evaluation of 5-Aminosalicylic Acid Derivatives
Applied SciencesThe anti-inflammatory scaffold 5-aminosalicylic acid, which is widely used in therapeutic applications, was chosen for the synthesis of N-[3-(hydrazinecarbonyl)-4-hydroxyphenyl]acetamide (1) to enhance its antibacterial properties.
Kazimieras Anusevičius +6 more
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