Results 81 to 90 of about 5,507 (218)
Beilstein Journal of Organic Chemistry, 2015 Glycogen phosporylase (GP) is a promising target for the control of glycaemia. The design of inhibitors binding at the catalytic site has been accomplished through various families of glucose-based derivatives such as oxadiazoles.
Marion Donnier-Maréchal +6 more
doaj +1 more source
The CF3 group attached to N-aryl hydrazone could be activated upon treatment with a suitable base, thus serving as an excellent C1 unit for the assembly of a series of 1,3,4-oxadiazoles by reaction with hydrazides.
Fangyi Li (1566442) +5 more
core +1 more source
ChemMedChem, Volume 21, Issue 8, 28 April 2026.Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti +9 more
wiley +1 more source
Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles
, 2016 We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SNAr substitution using phosphonium reagents (e.g., BOP).
Zhao-Kui Wan (2004907) +1 more
core +2 more sources
Oxadiazoles as potential drugs [PDF]
, 2016 Charles University in Prague, Faculty of Pharmacy in Hradec Králové Candidate: Pavlína Dzámová Supervisor: PharmDr. Marta Kučerová, Ph. D. Title of diploma thesis: Oxadiazoles as Potential Drugs Due to the increasing resistence of bacteria and fungi ...
Dzámová, Pavlína
core
Advanced Functional Materials, Volume 36, Issue 28, 7 April 2026.Materials exist that are useful for gamma scintillation, radiation shielding, neutron‐gamma pulse shape discrimination (PSD), thermal neutron detection, or high refractive index applications. While certain materials have exhibited optimal performance for each of these applications, none achieve multiple functions.
Isabelle Winardi +13 more
wiley +1 more source
Multifunctional Oxadiazole‐Based Polycatenars: A Pathway to Polar Columnar Phases
Advanced Materials Interfaces, Volume 13, Issue 7, 7 April 2026.Aromatic core fluorination directs oxadiazole‐based polycatenars into ferroelectric and antiferroelectric columnar phases with supergelation and photo‐responsiveness. ABSTRACT Polar columnar liquid crystals (LCs) offer a promising pathway to nanostructured architectures for next‐generation ferroelectric devices.
Yu Cao +7 more
wiley +1 more source
ChemMedChemAbstractTuberculosis remains a leading global health threat, exacerbated by the emergence of multi‐drug‐resistant strains. The search for novel therapeutic agents is critical in addressing this challenge. This review systematically summarizes the potential of oxadiazole derivatives as promising candidates in antimycobacterial drug discovery.
openaire +2 more sources
Tandem Reactions of 1,2,4-Oxadiazoles with Allylamines
, 2016 A reaction of 3-chloro-1,2,4-oxadiazoles with allylamine and diallylamine has been investigated. 3,3a,4,5-Tetrahydroisoxazolo[3,4-d]pyrimidines are produced through a tandem ANRORC/[3 + 2]cycloaddition pathway consisting of the addition of allylamine to ...
Antonio Palumbo Piccionello (564720) +2 more
core +1 more source
Molecules, 2011 A series of 5-substituted-4-amino-1,2,4-triazole-3-thioesters was synthesized by converting variously substituted organic acids successively into the corresponding esters, hydrazides, 5-substituted-1,3,4-oxadiazole-2-thiols, 5-substituted-1,2,4-triazole ...
Aurangzeb Hasan +2 more
doaj +1 more source