Results 81 to 90 of about 3,484 (169)

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

Chronic dietary oxalate nephropathy after intensive dietary weight loss regimen [PDF]

, 2017
Background: Hyperoxaluria has been associated with nephrolithiasis as well as acute and chronic kidney disease. We present a case of end stage renal failure caused by excessive dietary oxalate intake in a dietary weight loss regimen. Case Presentation: A
Bahar Bastani, Meher S Mallick, Gebran Khneizer, Ahmad Al-Taee   +3 more
core   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Thermal Induced Changes in Cuticle and Cortex to Chemically Treated Hair

Biopolymers, Volume 117, Issue 1, January 2026.
ABSTRACT The deterioration of the cuticle and cortex hair due to routine cosmetic practices has been identified as a primary factor contributing to undesirable changes in the esthetic qualities of hair. Chemical and physical treatments can cause significant damage to hair fibers.
C. R. R. C. Lima, A. C. C. Bandeira, T. S. Martins, L. Otubo, C. L. P. Oliveira   +4 more
wiley   +1 more source

Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering macrophages vulnerable to necroptosis

Cell Death and Disease
Several forms of regulated necrosis contribute to the pathogenesis of crystal nephropathy, however, the role of pyroptosis, an inflammatory form of cell death involving the formation of gasdermin-D pores in internal and external cell membranes, in this ...
Yoshihiro Kusunoki, Chenyu Li, Hao Long, Kanako Watanabe-Kusunoki, Meisi Kuang, Julian Aurelio Marschner, Andreas Linkermann, Stefanie Steiger, Hans-Joachim Anders   +8 more
doaj   +1 more source

Dysmetabolic nephropathy as a risk factor of pylonephritis in children

Zdorovʹe Rebenka, 2018
Background. Dysmetabolic nephropathies contribute to the development of urinary stone disease in children, the emergence of an infection of the urinary system, secondary pyelonephritis and formation of tubulo-interstitial changes in the kidneys. The main
L.I. Vakulenko
doaj   +1 more source

Association of Hyperlipidemia on the Prevalence and Risk Factors of Kidney Stones and Hypertension

Advances in Urology, Volume 2026, Issue 1, 2026.
Background This study aimed to assess the risk of kidney stones in a hyperlipidemic population and explore the development risk and related indicators with or without hypertension. Methods A cross‐sectional study included 1000 hyperlipidemic patients from Nanshan District Medical Group Headquarters, Shenzhen, 2021.
Jie Luo, Kaizhao Chen, Lijun Peng, Peizhong Liu, Wei Chen, Honglei Zhao, Mohammad H. Ather   +6 more
wiley   +1 more source

Hypermetabolism and Lipid Alterations Postburn: A Cardiovascular Perspective

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Severe thermal burns involving ≥ 20% of total body surface area (TBSA) initiate a distinct, prolonged physiological cascade extending well beyond the acute phase. This dysregulated response features chronic hypermetabolism, lipid remodeling, and sustained cardiovascular stress.
Mohammed AbuBaha, Ameer Awashra, Bara AbuBaha, Anwar Zahran, Mohammad Bdair, Dana Sandouka, Sarah Saife, Bara Sawalmeh, Amr Awad, Abdalhakim Shubietah, Arquimedes Gasparotto Junior   +10 more
wiley   +1 more source

Treatment for knee osteoarthritis in patients with oxalate nephropathy

Terapevticheskii arkhiv, 2015
To elucidate the safety profile and symptom-modifying effect of Alflutop and diacerein in the treatment of Kellgren-Lawrence Stages II-III knee osteoarthrosis (OA) in patients with oxalate nephropathy and Stages I-II chronic kidney disease (CKD) and to refine the effect of these drugs on urinary syndrome and renal function as compared to a response to ...
N V Voronina, N P Slutskaya, O I Markina, L P Kovalskaya, T B Agievich, D D Gelmutdinov, A V Bushina   +6 more
openaire   +3 more sources

Development and characterization of a pseudo multiple reaction monitoring method for the quantification of human uromodulin in urine. [PDF]

, 2016
BACKGROUND: Uromodulin is the most abundant protein in healthy human urine. Recently it has been suggested as a specific biomarker of renal tubular damage.
Hammond, Thomas G., Moes, Suzette, Devuyst, Olivier, Jenö, Paul, Hammond, Thomas G, Jennings, Paul, Odermatt, Alex, Youhanna, Sonia   +7 more
core   +1 more source