Results 11 to 20 of about 2,548 (196)
Bone marrow oxalosis: An unusual cause of cytopenia in end-stage renal disease; report of two cases
Indian Journal of Pathology and Microbiology, 2018 Systemic oxalosis can be either primary or secondary hyperoxaluria. Oxalosis is a phenomenon in which calcium oxalate crystals deposit in various visceral organs leading to bone marrow (BM) failure and recurrent renal stones.
Seema Sharma +3 more
doaj +2 more sources
Primary Hyperoxaluria Type 1 Diagnosed After Kidney Transplantation in the Absence of Classical Features. [PDF]
Case Rep NephrolBackground Primary hyperoxaluria Type 1 is a rare inherited metabolic disorder caused by pathogenic variants in the AGXT gene. Because the disorder leads to excessive internal oxalate formation, progressive end‐stage kidney disease (ESKD) may occur. While most affected individuals present during childhood, a subset is diagnosed only later in adult life,
Sultan R +5 more
europepmc +2 more sources
Fatal outcome of infantile oxalosis: case reports from three families and a review of literature
The Turkish Journal of Pediatrics, 1998 Infantile oxalosis is a rare, autosomal recessive disorder. We present three unrelated cases of infantile oxalosis and their families, emphasizing its place as a cause of acute renal failure in infancy, and showing the clinical heterogeneity of ...
A Oner +4 more
doaj +2 more sources
Isolated Kidney Transplant in Primary Hyperoxaluria-1 Enabled by Small Interfering RNA (siRNA) Therapy. Is It Time for Change? Case Report and Review of the Literature. [PDF]
Pediatr TransplantABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by excessive oxalate production that leads to nephrocalcinosis or nephrolithiasis and progressive kidney failure, associated with systemic oxalosis that is not reversed by dialysis. Pharmacological treatment is limited.
Habeeb SM +8 more
europepmc +2 more sources
Surgical Management of Pediatric Primary Hyperoxaluria Type 1: An Eight-Patient Case Series in the Pre-siRNA Era. [PDF]
Pediatr TransplantABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder that leads to systemic oxalosis and end‐stage renal disease (ESRD). Before the advent of siRNA therapy, liver transplantation, often combined with kidney transplantation, was the only definitive treatment.
Finer G +5 more
europepmc +2 more sources
JIMD Reports, 2021 Primary hyperoxaluria (PH) is a group of diseases due to mutations in genes coding for enzymes involved in oxalate metabolism. Three types of PH are identified depending on the gene mutated.
Matthieu Halfon +7 more
doaj +1 more source
Kaleidoscopic Views in the Bone Marrow: Oxalate Crystals in a Patient Presenting with Bicytopenia
Turkish Journal of Hematology, 2016 Pancytopenia associated with BM infiltration of different deposits is a rare condition mostly associated with amyloidosis or the accumulation of iron. One of the rarest deposits in the BM is oxalate crystals due to hyperoxaluria [1,2,3].
Yelda Dere +6 more
doaj +2 more sources
BMC Nephrology, 2020 Background Xylitol is an approved food additive that is widely used as a sweetener in many manufactured products. It is also used in pharmaceuticals. Secondary oxalosis resulting from high dietary oxalate has been reported.
Shinobu Takayasu +10 more
doaj +1 more source