Results 51 to 60 of about 2,548 (196)

Incidence and Risk Factors of Primary Arteriovenous Access Failure in Dialysis Patients: A National‐Based Retrospective Cohort Study

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aim The demand for hemodialysis (HD) among patients with end‐stage kidney disease (ESKD) is rising globally. A well‐functioning vascular access (VA) is crucial for effective dialysis therapy. This study aims to determine the incidence and risk factors of primary arterio‐venous access (AVA) maturation failure in HD patients ...
Tarek A. Ghonimi, Abdullah Hamad, Musaab Elgaali, Mohamed Farid, Mohamed Ezat, Rania A/Aziz, Mohamed Amin, Hassan Al‐Malki, Mohamad Alkadi   +8 more
wiley   +1 more source

18-Fluorodeoxyglucose positron emission computed tomography for systemic oxalosis in primary hyperoxaluria type 1.

, 2022
To the Editor: Primary hyperoxaluria type 1 (PH1) is associated with hepatic overproduction of oxalate. Kidneys gradually become unable to eliminate excess oxalate, leading to systemic oxalosis (SO) with deposits in organs.1 When kidney transplantation ...
Kanaan, Nada, Devresse, Arnaud, Lhommel, Renaud, Godefroid, Nathalie, Goffin, Eric   +4 more
core   +1 more source

Tocilizumab as Adjuvant Therapy in Refractory Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients

Pediatric Transplantation, Volume 29, Issue 6, September 2025.
ABSTRACT Background Antibody mediated rejection (ABMR) is a major cause of graft loss in kidney transplantation. There are limited treatment options with poor efficacy. Intravenous tocilizumab has been reported to be of benefit in a small number of patients.
Anne M. Durkan, Melanie Aldridge, Stephen I Alexander, Deirdre Hahn   +3 more
wiley   +1 more source

A Minor Haplotype Variant Determines the Pathogenicity of the p.Ile279Thr Substitution in the Primary Hyperoxaluria Type 1 Gene, AGXT

Journal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT Human alanine:glyoxylate aminotransferase (AGT) is a liver peroxisomal enzyme that metabolizes glyoxylate, the oxalate precursor, to glycine. AGT deficiency, due to recessive pathogenic changes in the AGXT gene, results in calcium oxalate accumulation and kidney stones, a condition known as primary hyperoxaluria type 1 (PH1).
Luana Ruta, Andrea G. Cogal, Gioena Pampalone, David J. Sas, John C. Lieske, Gill Rumsby, Barbara Cellini, Peter C. Harris   +7 more
wiley   +1 more source

Systemic Oxalosis in Infants: Two Cases and Literature Review

, 2013
The infantile form of primary hyperoxaluria is a very rare disease and often presents as a life-threatening condition because of rapid progression to end-stage renal disease and systemic oxalosis.
Hakan Poyrazoglu, Hulya Akgun, Tulpar, Sebahat, Poyrazoglu, Hakan, Dusunsel, Ruhan, Ruhan Dusunsel, Akgun, Hlya, Gunduz, Zubeyde, Sebahat Tulpar, Zubeyde Gunduz, Funda Bastug, Bastug, Funda   +11 more
core   +1 more source

Oxalosis and Livedo Reticularis

Actas Dermo-Sifiliográficas (English Edition), 2013
Oxalosis is a disease caused by the deposition of calcium oxalate in extrarenal tissues, most commonly bone, myocardium, retina, blood vessels, and skin, causing the clinical manifestations of the disease. Involvement of the blood vessels of the skin can give rise to livedo reticularis, acrocyanosis, ulcers, and gangrene.
E, Jorquera-Barquero, M C, Súarez-Marrero, F, Fernández Girón, J J, Borrero Martín   +3 more
openaire   +2 more sources

A Brief History of Inherited Metabolic Diseases: A Personal 60 Years Clinical Flashback

Journal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT The concept of IMDs has evolved over a century from rare deficits in amino acid catabolism diagnosed by the accumulation of biochemical markers such as phenylketonuria (PKU) to diseases affecting organelle metabolism, synthesis of complex molecules, and cellular trafficking.
Jean‐Marie Saudubray, Manuel Schiff
wiley   +1 more source

Diagnosis of Inherited Metabolic Disease in Older Patients: A Systematic Literature Review

Journal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.
ABSTRACT Inherited metabolic diseases (IMDs) are genetic disorders that disrupt biochemical processes in the human body, due to pathogenic variants in genes encoding enzymes or transporters. While IMDs are mostly diagnosed in infancy or childhood, there is an increasing number of diagnoses in adult patients.
Maria‐Rita Moio, Julia Cordeiro Milke, Yannick Moutapam‐Ngamby‐Adriaansen, Arthur Minas Alberti, Marie Gernay, Eduardo Augusto Schutz, Ida Vanessa Doederlein Schwartz, François Maillot   +7 more
wiley   +1 more source

Systemic Oxalosis in Infants: Two Cases and Literature Review

Turkish Journal of Nephrology, 2019
The infantile form of primary hyperoxaluria is a very rare disease and often presents as a lifethreatening condition because of rapid progression to end-stage renal disease and systemic oxalosis.
Zübeyde GÜNDÜZ, Funda BAŞTUĞ, Sebahat TÜLPAR, Hakan POYRAZOĞLU, Hülya AKGÜN, Ruhan DÜŞÜNSEL   +5 more
doaj  

An Interactive Computational Pipeline to Investigate Ventricular Hemodynamics with Real‐Time Three‐Dimensional Echocardiography and Computational Fluid Dynamics

Engineering Reports, Volume 7, Issue 1, January 2025.
In this work, we develop an interactive pipeline for geometry preparation of moving mesh simulations of cardiac hemodynamics. The open source tool is easy to use and can be seamlessly integrated into downstream CFD workflows. ABSTRACT Blood flow within the ventricle can provide important information on the performance of the heart. The determined blood
Jan‐Niklas Thiel, Daniel Verhülsdonk, Ulrich Steinseifer, Katharina Linden, Ulrike Herberg, Ingeborg Friehs, Daniel Diaz‐Gil, Michael Neidlin   +7 more
wiley   +1 more source