Results 101 to 110 of about 7,946 (266)

Synthesis of rigid p-terphenyl-linked carbohydrate mimetics

open access: yesBeilstein Journal of Organic Chemistry, 2014
An approach to β-D-2-aminotalose- and β-D-2-aminoidose-configured carbohydrate mimetics bearing a phenyl substituent is described. Unnatural divalent rigid p-terphenyl-linked C-aryl glycosides with 2.0 nm dimension are available using Suzuki cross ...
Maja Kandziora, Hans-Ulrich Reissig
doaj   +1 more source

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

open access: yesBMC Cancer, 2017
Background Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer ...
C. P. Baburajeev   +9 more
doaj   +1 more source

Synthesis of some Dihydrobenz (1,3) oxazine Derivatives [PDF]

open access: green, 1970
P. B. Talukdar   +2 more
openalex   +1 more source

New Chemistry of Donor-Acceptor Cycloalkanes and Studies Towards the Synthesis of Streptorubin B [PDF]

open access: yes, 2016
This dissertation presents two separate chapters within the broad area of synthetic organic chemistry. The first chapter describes the annelation chemistry of donor-acceptor (DA) cyclopropanes and cyclobutanes for the synthesis of heterocycles.
Vemula, Naresh
core   +1 more source

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

open access: yesBiotechnology Reports, 2020
Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma ...
Chaithanya Somu   +13 more
doaj  

(A) 2:3-Dihydro-3-Oxobenz-1:4-Oxazines. (B) A Note on Lycorine [PDF]

open access: yes, 1954
Part I. The chemistry of the 2:3-dihydro-3-oxo-benz-1:4-oxazines is reviewed, and a general method for their N-methylation developed. The possession of a feebly reactive methylene group is demonstrated in the formation of a benzylidene derivative by 2:3 ...
Ogg, James
core  

Synthesis of new enantiopure poly(hydroxy)aminooxepanes as building blocks for multivalent carbohydrate mimetics

open access: yesBeilstein Journal of Organic Chemistry, 2014
New compounds with carbohydrate-similar structure (carbohydrate mimetics) are presented in this article. Starting from enantiopure nitrones and lithiated TMSE-allene we prepared three 1,2-oxazine derivatives which underwent a highly stereoselective Lewis
Léa Bouché   +2 more
doaj   +1 more source

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