Results 51 to 60 of about 11,541 (257)
Arabian Journal of Chemistry, 2017 The antimicrobial activity of 1,3-disubstituted-1H-naphtho[1,2-e][1,3]oxazines was correlated with their physicochemical parameters using Hansch analysis for first time. The QSAR models were developed by both linear and multiple linear regression and the
Vikas Verma +3 more
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Chemistry – A European Journal, EarlyView.Fused nitrogen‐bridgehead N,O‐acetals receive specific emphasis as pivotal scaffolds due to their significant role in the bioactivity of medicinally relevant molecules. Significant approaches have been reported on their role as key synthetic building blocks/motifs in the construction of complex organic molecules and their utility as chiral auxiliaries ...
Alexis D. Kouvelas +2 more
wiley +1 more source
Journal of Chemistry, 2016 The hitherto unknown 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 1a was synthesized. Both 1a and its 2,4 dichlorophenyl derivative 1b were utilized as building blocks for the preparation of novel class of ...
A. K. Elziaty +4 more
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Stereoselective Synthesis and Cytoselective Toxicity of Monoterpene-Fused 2-Imino-1,3-thiazines
Molecules, 2014 Starting from pinane-, apopinane- and carane-based 1,3-amino alcohols obtained from monoterpene-based β-amino acids, a library of monoterpene-fused 2-imino-1,3-thiazines as main products and 2-thioxo-1,3-oxazines as side-products were prepared via two ...
Zsolt Szakonyi +3 more
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BMC Chemistry, 2022 A series of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines (S 1 –S 11 ) were synthesized with an eco-friendly and recoverable nanocatalyst (GO-Fe3O4–Ti(IV)) as an efficient magnetic composite. The new nanocatalyst was characterized by FT-IR, XRD
Soghra Khabnadideh +8 more
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Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
Chemistry – A European Journal, EarlyView.This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile +4 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.The core of an HTI photoswitch with different oxidation states of the sulfur heteroatom was modified by introducing aldehydes and carboxylic acid substituents for tailored absorption, quantum yields, and thermal stability. Notably, the substituted HTIs enabled high isomerization yields, while sulfur oxidation enhanced quantum yields but reduces ...
Matías I. Quindt +6 more
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Synthesis of Substituted Pyrido-oxazine through Tandem SN2 and SNAr Reaction
SynOpen, 2018 Pyrido-oxazine derivatives have been synthesized by employing tandem SN2 and SNAr reaction between 2,4,6-tribromo-3-(2-bromoethoxy)pyridine or 2,4,6-tribromo-3-(3-bromopropoxy)pyridine and a variety of primary amines. Moderate to good regioselectivity in
Mosim Amin Pathan, Faiz Ahmed Khan
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ChemMedChem, Accepted Article.To search for new antitubercular agents, we have designed, synthesized, and evaluated a series of 1,4‐benzoxazinone‐based compounds. These molecules showed potent antimycobacterial activity, with MIC between 2 and 8 μg/mL. This interesting profile included activity against several drug‐resistant strains and minimal cytotoxicity against mammalian Vero ...
Daniele Zampieri +6 more
wiley +1 more source
Chemical Physics Impact, 2022 Silver nanoparticles (AgNPs) were synthesized through greener route using the Ethanol extract of Clerodendrum colebrookianum leaves. The synthesized AgNPs were characterized and confirmed through using various analytical studies like FT-IR, UV–vis, XRD ...
Putusenla Imchen +3 more
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