Results 41 to 50 of about 913 (183)
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Photochemical reactions of substituted 2(3H)-oxazolones with carbonyl compounds
Photocycloaddition of carbonyl compounds of various triplet energy to 3-acetyl-2(3H)-oxazolone (V) and 3-acetyl-4,5-dimethyl-2(3H)-oxazolone (VI) afforded oxetanes XIII-XX. Other investigated 2(3H)-oxazolones VII-IX gave no oxetanes.
Jan Kopecký +2 more
core +1 more source
The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid +3 more
wiley +1 more source
Structure and codes of the synthesized oxazolones and imidazolones.
Structure and codes of the synthesized oxazolones and imidazolones.
Hanan A. Assiri (3626405) +4 more
core +1 more source
The zwitterionic imidazolium salt was prepared and characterized by 1H NMR. It was first used for synthesis of azlactones via Erlenmeyer synthesis from aromatic aldehydes and hippuric acid under solvent-free conditions.
Baocheng Zhou, Wenxing Chen
doaj +1 more source
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber +8 more
wiley +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source
A sustainable approach for the Erlenmeyer synthesis of azlactones in deep eutectic solvents
Deep eutectic solvents (DESs) have emerged as promising alternatives to hazardous catalysts and solvents in various chemical transformations. This study presents a facile, green, and simple approach for the synthesis of azlactones using a novel DES ...
Fatemeh Mohammad +3 more
doaj +1 more source
Initial OX40–OX40L Signaling Promotes a Skin‐Resident Memory T‐Cell Reservoir in Atopic Dermatitis
Allergy, EarlyView.
Takayoshi Komatsu‐Fujii +6 more
wiley +1 more source
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source

