Results 51 to 60 of about 572,637 (334)

The oxidation-reduction potential of coenzyme I [PDF]

, 1940
The oxidation-reduction potential of cozymase (diphosphopyridine nucleotide) was calculated from the free energies of formation of aqueous d-alanine and d-glutamic acid based on thermal data, and the equilibria measured by Wurmser and Filitti-Wurmser(1 ...
Borsook, Henry
core  

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Teaching the concepts of oxidation and reduction contextualized in the study of corrosion

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2013
The contextualization of chemistry is of great importance to our society as it allows to bring this science to students of secondary education thus facilitating the learning process, so that students can identify and explain the phenomena that occur ...
Lazo Santibáñez, Leontina, Vidal Fuentes, Jorge, Vera Aravena, Rosa   +2 more
doaj  

Methane oxidation linked to chlorite dismutation.

Frontiers in Microbiology, 2014
We examined the potential for CH4 oxidation to be coupled with oxygen derived from the dissimilatory reduction of perchlorate, chlorate or via chlorite (ClO2-) dismutation.
Laurence G. Miller, Shaun M. Baesman, Charlotte I. Carlstrom, John D. Coates, Ronald S. Oremland   +4 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Formulated plastic separators for soluble electrode cells [PDF]

, 1979
The fabrication and milling of membranes comprising a hydrochloric acid-insoluble sheet of a mixture of a rubber and a powdered ion transport material are described. The sheet can be present as a coating upon a flexible and porous substrate.
Sheibley, D. W.
core   +1 more source

Measurement of the ground-state distributions in bistable mechanically interlocked molecules using slow scan rate cyclic voltammetry [PDF]

, 2011
In donor–acceptor mechanically interlocked molecules that exhibit bistability, the relative populations of the translational isomers—present, for example, in a bistable [2]rotaxane, as well as in a couple of bistable [2]catenanes of the donor–acceptor ...
Barin, Gokhan, Barnes, Jonathan C., Basuray, Ashish N., Benitez, Diego, Dey, Sanjeev K., Fahrenbach, Albert C., Fang, Lei, Goddard, William A., III, Li, Hao, Stoddart, J. Fraser, Sue, Chi-Hau   +10 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Deoxygenation of Graphene Oxide: Reduction or Cleaning? [PDF]

Chemistry of Materials, 2013
We show that the two-component model of graphene oxide (GO), that is, composed of highly oxidized carbonaceous debris complexed to oxygen functionalized graphene sheets, is a generic feature of the synthesis of GO, independent of oxidant or protocol used. The debris present, roughly one-third by mass, can be removed by a base wash.
Thomas, H.R., Day, S.P., Woodruff, W.E., Vallés, C., Young, R.J., Kinloch, I.A., Morley, G.W., Hanna, J.V., Wilson, N.R., Rourke, J.P.   +9 more
openaire   +3 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source