Results 61 to 70 of about 572,637 (334)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Electrochemical processes and systems: application for tutors [PDF]

open access: yes, 2018
The features of redox reactions and the principles of their balancing according to the medium composition are considered. The basic representations about electrochemical processes and systems are outlined. The reactions and principles of chemical sources
Karakurkchi, A.   +4 more
core   +1 more source

High Throughput Screening and QSAR-3D/CoMFA: Useful Tools to Design Predictive Models of Substrate Specificity for Biocatalystsâ€

open access: yesMolecules, 2004
After a hierarchical microbial screening process, new microorganisms have been discovered that act as biocatalysts for the stereoselective oxidation of secondary alcohols or for ketone reduction.
J. V. Sinisterra   +3 more
doaj   +1 more source

Optimization of parameters for the dissolution of Mn from manganese nodules with the use of tailings in an acid medium [PDF]

open access: yes, 2019
Manganese nodules are an attractive source of base metals and critical and rare elements and are required to meet a high demand of today’s industry. In previous studies, it has been shown that high concentrations of reducing agent (Fe) in the system are ...
Castillo Segura, Jonathan Alejandro   +6 more
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Application of oxidation-reduction potential in microbial fermentation [PDF]

open access: yesZhongguo niangzao
Oxidation-reduction potential (ORP), as a highly sensitive fermentation parameter that can monitor the fermentation status in real time, can be applied to fermentation by overcoming the limitations of the application of dissolved oxygen electrodes under ...
LI Zixiang, YI Dong, JIANG Shuiqin, CHEN Daijie, TAN Jun
doaj   +1 more source

Study of actinide chemistry in saturated potassium fluoride solution [PDF]

open access: yes, 1969
Study concerning the chemistry of actinides in saturated KF solution included work with neptunium, uranium, and americium. Solubilities, absorption spectra, oxidation-reduction reactions, and solid compounds which can be produced in KF solution were ...
Cohen, D., Thalmayer, C. E.
core   +1 more source

Active Carboxylic Acid-Terminated Alkanethiol Self-Assembled Monolayers on Gold Bead Electrodes for Immobilization of Cytochromes c [PDF]

open access: yes, 2002
It is extremely difficult to immobilize cytochrome c (cyt c) on carboxylic acid-terminated alkanethiol self-assembled monolayers (HOOC-SAM) on gold bead electrodes prepared in a hydrogen flame.
Gray, Harry B.   +5 more
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Electrochemical data of ferrocenylsubphthalocyanine dyads

open access: yesData in Brief, 2020
The data presented in this paper is related to the research article entitled “Synthesis, Spectroscopy, Electrochemistry and DFT of Electron-Rich Ferrocenylsubphthalocyanines” [1] where electrochemical redox data and cyclic voltammograms at only a scan ...
Pieter J. Swarts, Jeanet Conradie
doaj   +1 more source

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