Results 151 to 160 of about 2,049,340 (295)
(+)-(S-Methyl-
R. L. M. Synge, Joseph Wood
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Total Conjugation of Linoleic Acid in Oxidation with Lipoxidase [PDF]
Sune Bergström, Ralph T. Holman
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The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Wafer-scale uniformity improvement of Dolan-bridge Josephson junction by shadow evaporation bias correction. [PDF]
Moskaleva DA+9 more
europepmc +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Chemical Synthesis of Crustacean Insulin-Like Peptide Using a Novel Method to Prevent Methionine Oxidation During Solid Phase Peptide Synthesis. [PDF]
Katayama H, Tsutsui N.
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The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Effect of Oxidation and Silane Modifications Applied to the Bonded Material and Fibers in Carbon-Fiber-Reinforced Composite Adhesive Joints. [PDF]
Akpinar IA, Koçyiğit ÖF, Atasoy S.
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