Results 41 to 50 of about 154,148 (225)

Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]

, 2020
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian, Clarke, Clare L., Gandy, Stephen, George, Jacob, Gingles, Christopher, Hutcheon, Anita, Nicholas, Richard S., Priba, Lukasz, Struthers, Allan D., Sumukadas, Deepa, Witham, Miles D.   +10 more
core   +2 more sources

Neutrophil gelatinase-associated lipocalin: its response to hypoxia and association with acute mountain sickness. [PDF]

, 2013
Acute Mountain Sickness (AMS) is a common clinical challenge at high altitude (HA). A point-of-care biochemical marker for AMS could have widespread utility.
Begley, J, Boos, C, Hooper, T, King, R, Mellor, A, O'Hara, J, Piper, R, Smith, C, Stacey, M, Turner, S, Woods, DR, Yarker, J   +11 more
core   +2 more sources

Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis. [PDF]

, 2013
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with no effective treatment to date. Despite its multi-factorial aetiology, oxidative stress is hypothesized to be one of the key pathogenic mechanisms.
Azzouz, M, Higginbottom, A, Nanou, A, Ning, K, Shaw, P, Valori, CF, Wyles, M   +6 more
core   +1 more source

The association between oxidative balance score and periodontitis in adults: a population-based study

Frontiers in Nutrition, 2023
IntroductionThe pathogenesis between oxidative stress and periodontitis was correlated. The Oxidative Balance Score (OBS) is a systematic tool to assess the effects of diet and lifestyle in relation to oxidative stress.
Haitao Qu
doaj   +1 more source

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia. [PDF]

, 2014
Inherited deficiency in the mitochondrial protein frataxin (FXN) causes the rare disease Friedreich's ataxia (FA), for which there is no successful treatment. We identified a redox deficiency in FA cells and used this to model the disease.
Al-Mahdawi, Al-Mahdawi, Al-Mahdawi, Albano, Bidichandani, Brandon Brown, Brian D. Scott, Bridwell-Rabb, Campuzano, Catterall, Chantrel-Groussard, Chorley, Chutake, Condò, Cossée, Cox, De Biase, Deutsch, Drechsel, Dürr, Fahey, Filla, Florestano, Frank, Friedman, Gino A. Cortopassi, Greene, Hashemy, Heike Wulff, Huang, Kalinin, Kensler, Kim, Kim, Koeppen, Koeppen, Kosower, Kosower, Kruger, Lai, Larkin, Liu, Lopert, Lu, Lu, Marissa Z. McMackin, Mark A. Pook, Miranda, Mittal Jasoliya, Montermini, Osburn, Paredes-Gonzalez, Paupe, Riah, Sandi, Sangster, Saveliev, Schmitz-Hübsch, Selak, Shan, Shan, Shan, Shelmire, Sinha, Streck, Subramaniam, Sunil Sahdeo, Susan L. Perlman, Tan, Tan, Tella, Verdon, Wang, Wang, Weaver, Willis, Yang, Yu, Zhang   +78 more
core   +1 more source

Association between oxidative balance score and new-onset hypertension in adults: A community-based prospective cohort study

Frontiers in Nutrition, 2022
IntroductionOxidative stress plays a key role in the pathophysiology of hypertension development. The oxidative balance score (OBS) comprises dietary and lifestyle pro- and anti-oxidant components and reflects the overall oxidative stress burden.
Jun-Hyuk Lee, Jun-Hyuk Lee, Da-Hye Son, Yu-Jin Kwon   +3 more
doaj   +1 more source

Airways oxidative stress, lung function and cognitive impairment in aging. [PDF]

, 2010
BACKGROUND: An altered balance of oxidants/antioxidants is one of the pathological mechanisms of many age-dependent disorders. We aimed to investigate the age-related airways oxidative stress, using non invasive, safe and repeatable techniques; to ...
Cagnazzo, Mg, Carpagnano, Ge, Foschino Barbaro, M. P., Gramiccioni, C, Spanevello, Antonio, Turchiarelli, V   +5 more
core   +1 more source

Association between the Oxidative Balance Score and Incident Chronic Kidney Disease in Adults

Antioxidants, 2023
Oxidative stress is a novel risk factor for chronic kidney disease (CKD). The oxidative balance score (OBS) was developed to represent the overall oxidative balance based on dietary and lifestyle pro-oxidant and antioxidant components. The aim of this study is to verify the relationship between the OBS and the incidence of CKD.
Da-Hye Son, Hye Sun Lee, So-Young Seol, Yong-Jae Lee, Jun-Hyuk Lee   +4 more
openaire   +4 more sources

Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]

, 2018
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia, Giovannetti, Antonello, Malorni, Walter, Pietraforte, Donatella, Straface, Elisabetta, Vona, Rosa   +5 more
core   +1 more source

Oxidative stress in endurance flight: an unconsidered factor in bird migration [PDF]

, 2014
Migrating birds perform extraordinary endurance flights, up to 200 h non-stop, at a very high metabolic rate and while fasting. Such an intense and prolonged physical activity is normally associated with an increased production of reactive oxygen and ...
Costantini, David, Jenni, Lukas, Jenni-Eiermann, Susanne, Smith, Shona   +3 more
core   +6 more sources