Results 131 to 140 of about 309,295 (244)

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source

Using novel oxidative phosphorylation inhibitors to attenuate drug resistance in human gliomas. [PDF]

EXCLI J
Tsai CK, Lin CY, Chang YL, Yang FC, Chou CH, Huang YC, Hueng DY.   +6 more
europepmc   +1 more source

Regulation of the Metabolism of Rabbit Liver Mitochondria by Long Chain Fatty Acids and Other Uncouplers of Oxidative Phosphorylation

, 1969
E.Jack Davis, D. M. Gibson
openalex   +1 more source

Properties of substituted 2-trifluoromethylbenzimidazoles as uncouplers of oxidative phosphorylation [PDF]

, 1967
OTG Jones, WA Watson
openalex   +1 more source

GLUCOSE OXIDATION AND PHOSPHORYLATION [PDF]

Journal of Biological Chemistry, 1940
Carl F. Cori, Sidney P. Colowick, Mary Scott Welch   +2 more
openaire   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Galectin-3 in tumor-stromal cells enhances gemcitabine resistance in pancreatic adenocarcinoma by suppressing oxidative phosphorylation. [PDF]

Genes Dis
Wu Y, An G, Tong J, Zhang W, Tian Z, Dong B, Liu X, Zhao L, Ye C, Liu J, Zhao W, Ma H.   +11 more
europepmc   +1 more source

Identification of Phosphohistidine in Digests from a Probable Intermediate of Oxidative Phosphorylation

, 1962
Paul D. Boyer, M. DeLuca, K.E. Ebner, Donald E. Hultquist, J B Peter   +4 more
openalex   +1 more source

Incorporation of amino acids into the protein of isolated mitochondria. A search for optimum conditions and a relationship to oxidative phosphorylation [PDF]

, 1962
DES TRUMAN, A. Körner
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source