Results 131 to 140 of about 306,484 (171)

Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signaling and Oxidative Phosphorylation, Killing Acute Myeloid Leukemia Cells. [PDF]

open access: yesMol Cancer Ther
Gamma JM   +12 more
europepmc   +1 more source

HIF1 activation safeguards cortical bone formation against impaired oxidative phosphorylation. [PDF]

open access: yesJCI Insight
Khan MP   +10 more
europepmc   +1 more source
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Mechanism of Oxidative Phosphorylation

Nature, 1958
THE phenothiazine tranquillizer chlorpromazine has the following actions: (1) It inhibits electron transport between reduced diphosphopyridine nucleotide and cytochrome c in appropriate systems; the efficiency of the coupled phosphorylation is not affected. (2) Chlorpromazine is not effective in mitochondria treated with water or in non-phosphorylating
J. D. Judah   +5 more
openaire   +3 more sources

Efficiency of Oxidative Phosphorylation

Nature, 1954
THE quantitative yield of phosphate fixed during cellular oxidations deserves critical investigation, for it determines the efficiency with which utilizable energy may be derived from assimilated foodstuffs and it may influence metabolic regulatory mechanisms1. This problem has been the subject of many investigations (cf. Krebs et al.
J. H. Copenhaver, Henry A. Lardy
openaire   +3 more sources

Oxidative Phosphorylation in Mitochondria

Annual Review of Biochemistry, 1969
INTRODUCTION. • • • • • • • • • • • • • • • • • • • • • • • • • • • • . • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 991 ELECTRON TRANSPORT AND COUPLING SITES. • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 991 PROTEIN FACTORS THAT COUPLE RESPIRATION WITH PHOSPHORYLATION. • • • • • • • • • • 999 Phosphoryl tran rerases.
H A Lardy, S M Ferguson
openaire   +2 more sources

Oxidative phosphorylation and aging

Ageing Research Reviews, 2006
This review addresses the data that support the presence and contribution of decreased mitochondrial oxidative phosphorylation during aging to impaired cellular metabolism. Aging impairs substrate oxidation, decreases cellular energy production and increases the production of reactive intermediates that are toxic to the cell.
Edward J. Lesnefsky, Charles L. Hoppel
openaire   +2 more sources

Uncouplers of oxidation phosphorylation

Pharmacology & Therapeutics, 1980
Abstract Numerous compounds, covering a broad range of chemical structures, selectively interfere with the mitochondrial mechanism for transforming energy derived from oxidative metabolism into regeneration of ATP. Within some chemical classes, structure-activity correlations have been useful.
openaire   +4 more sources

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