Results 151 to 160 of about 350,577 (307)

Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death [PDF]

, 2018
Dong Guo, Wenting Xie, Pan Xiong, Huifang Li, Siqi Wang, Guimiao Chen, Yuehong Gao, Jiechao Zhou, Ye Zhang, Guojun Bu, Maoqiang Xue, Jie Zhang   +11 more
openalex   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

A biallelic MRPL42 variant causes a combined oxidative phosphorylation deficiency syndrome revealed by multi-omics. [PDF]

NPJ Genom Med
Boschann F, Kopp J, Römer S, Küchler O, Lyubenova H, von Kügelgen N, Hertstein E, Hagelstein L, Becker C, Becker K, Brachs S, Mai K, Meierhofer D, Seelow D, Mundlos S, Horn D, Schuelke M, Fischer-Zirnsak B.   +17 more
europepmc   +1 more source

Dietary chromium picolinate-promoted oxidative phosphorylation may be a potential mean to improve hypoxia tolerance of juvenile grass carp (Ctenopharyngodon idella)

Chuanshuai Xiong, Xiao‐Qiu Zhou, Lin Feng, Wei‐Dan Jiang, Yang Liu, Yao-Bin Ma, Hongmei Ren, Xiao‐Wan Jin, Jun Jiang, Pei Wu   +9 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Oxidative Phosphorylation in Uncoupled Mitochondria. [PDF]

Bioessays
Brunetta HS, Mori MA, Bartelt A.
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

The mechanisms of energy balance between oxidative phosphorylation and glycolysis in human ovarian granulosa cells. [PDF]

Front Physiol
Wang J, Wang GJ, Wang LC, Wang LL, Qin JJ, Wang B, Cui J, Wu HL, Li R, Liu W.   +9 more
europepmc   +1 more source

Oxidative phosphorylation is regulated by ubiquitination under slow-cooling treatment in hydrated lettuce (Lactuca sativa) seeds [PDF]

Y. W. Han, Wenchao Jiang, Xiuli Wang, Jie Wang, Danping Song, Wei‐Dong Yang, Baolin Liu   +6 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source