Results 141 to 150 of about 525,514 (363)
Selective advantage of aerobic glycolysis over oxidative phosphorylation [PDF]
arXivThe utilization of glycolysis in aerobic conditions have been a subject of debate for more than a century. A hypothesis supported by previous data is that glycolysis has a higher rate of ATP production per protein mass and per occupied volume than oxidative phosphorylation (OxPhos).
arxiv
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma [PDF]
arXiv, 2017 Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthesis. Understanding the metabolic reprogramming in cancer can help design therapies to target metabolism and thereby to improve prognosis.
arxiv
Effect of ugandensidial on mitochondrial oxidative phosphorylation
Bulletin of the Chemical Society of Ethiopia, 1993 BuII. Chem. Soc. Ethiop. 1993, 7(1), 17-21.
Mohamed S. Rajab, Julius O. Olowooker
doaj
In vivo multi-parametric imaging of metastatic and non-metastatic breast cancer [PDF]
, 2017 A current issue in cancer therapy is the characterization of metastatic tumors, which can increase ease of treatment and patient trials. We present an in vivo study of metastatic (4T1) and non-metastatic (4T1-TWIST KO) breast tumor sister cell lines to ...
Rasul, Raisa B
core +2 more sources
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
The effect of reducing ATP levels on reorientation of the secondary palate [PDF]
, 1986 The force for directing palate shelf reorientation appears to be associated with elements of the presumptive hard palate (Brinkley & Vickerman, 1979; Bulleit & Zimmerman, 1985).
Bulleit, Robert F., Zimmerman, Ernest F.
core
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
PLoS ONE, 2015 IntroductionNeuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation.
Raphael Johannes Morscher +7 more
doaj +1 more source
Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance. [PDF]
, 2019 A mammalian cell houses two genomes located separately in the nucleus and mitochondria. During evolution, communications and adaptations between these two genomes occur extensively to achieve and sustain homeostasis for cellular functions and ...
Jiang, Nian +3 more
core