Results 161 to 170 of about 309,295 (244)

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu, Hongxia Cheng, Jiacheng Yin, Yuansheng Zheng, Haochun Shi, Binyang Pan, Ming Li, Mengnan Zhao, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Guoshu Bi, Weigang Guo, Lin Wang, Yiwei Huang   +14 more
wiley   +1 more source

Macrophage Membrane-Coated Liposomes Delivering Vonoprazan Disrupt Mitochondrial Oxidative Phosphorylation in Diffuse Large B-Cell Lymphoma. [PDF]

Int J Nanomedicine
Wang W, Wang L, Fan Q, Xu J, Li Y, Xu J, Zhao B, Ge D, Xiong L, Wu Y, Zhu Y, Chen M.   +11 more
europepmc   +1 more source

MALMPS: A Machine Learning‐Based Metabolic Gene Prognostic Signature for Stratifying Clinical Outcomes and Molecular Heterogeneity in Stage II/III Colorectal Cancer

Advanced Science, EarlyView.
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen, Ze Wang, Chenglong Sun, Yang Zhong, Yuan Liu, Yikun Li, Tongchao Zhang, Yuan Zhang, Xingyu Zhu, Leping Li, Feifei Teng, Ming Lu, Wei Chong   +12 more
wiley   +1 more source

Partial Resolution of the Enzymes Catalyzing Oxidative Phosphorylation

, 1967
Gottfried Schatz, Harvey S. Penefsky, Efraim Racker   +2 more
openalex   +2 more sources

Oxidative Phosphorylation as a Predictive Biomarker of Oxaliplatin Response in Colorectal Cancer. [PDF]

Biomolecules
Martinez-Bernabe T, Pons DG, Oliver J, Sastre-Serra J.   +3 more
europepmc   +1 more source

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

Advanced Science, EarlyView.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan, Wei Yu, Xinggui Wen, Xiangdong Ding, Xiang Li   +4 more
wiley   +1 more source

IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia. [PDF]

Nat Commun
Horn S, Schmid M, Berest I, Piattini F, Zhang J, de Bock K, Devuyst O, Nlandu Khodo S, Kisielow J, Kopf M.   +9 more
europepmc   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

LRPPRC confers enhanced oxidative phosphorylation metabolism in triple-negative breast cancer and represents a therapeutic target. [PDF]

J Transl Med
Xue Q, Wang W, Liu J, Wang D, Zhang T, Shen T, Liu X, Wang X, Shao X, Zhou W, Fang X.   +10 more
europepmc   +1 more source

Partial Resolution of the Enzymes Catalyzing Oxidative Phosphorylation

, 1968
Bernard A. Bulos, E. Racker
openalex   +1 more source