Results 161 to 170 of about 3,781,647 (383)
Effects of Herbicides and Related Chemicals on Oxidation and Phosphorylation by Isolated Soybean Mitochondria. [PDF]
, 1957 C. M. Switzer
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Mitochondria: beyond oxidative phosphorylation
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1995 Mitochondria are essential eukaryotic organelles that perform many functions in addition to oxidative phosphorylation. Some of these functions are still poorly understood or as yet undiscovered, but may resemble already known functions in bacteria. The rapidly growing sequence information on bacterial genes, the polymerase chain reaction, and gene ...
openaire +3 more sources
Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague +8 more
wiley +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Oxidative phosphorylation in HIV-1 infection: impacts on cellular metabolism and immune function
Frontiers in ImmunologyHuman Immunodeficiency Virus Type 1 (HIV-1) presents significant challenges to the immune system, predominantly characterized by CD4+ T cell depletion, leading to Acquired Immunodeficiency Syndrome (AIDS).
Natalia Rodriguez Rodriguez +6 more
doaj +1 more source
Barbiturates and oxidative phosphorylation [PDF]
Biochemical Journal, 1960 W. N. Aldridge, V. H. Parker
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Oxidative phosphorylation by subcellular particles from yeast [PDF]
, 1958 M.F. Utter, D.B. Keech, Peter M Nossal
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