Results 11 to 20 of about 557,753 (336)

Oxidative Phosphorylation-Related Signature Participates in Cancer Development, and PTPRG Overexpression Suppresses the Cancer Progression in Clear Cell Renal Cell Carcinoma

open access: yesJournal of Immunology Research, 2022
Clear cell renal cell carcinoma (ccRCC) was a common cancer type diagnosed with frequent metastases, harboring an unfavorable therapeutic response, and results in a poor prognosis.
Liang Huang   +4 more
doaj   +1 more source

Low level of mancozeb exposure affects ovary in mice

open access: yesEcotoxicology and Environmental Safety, 2022
Mancozeb (MCZ) is widely used as a protective fungicide. This study aimed to explore the effects of low level MCZ exposure on ovary in mice. Twenty Kunming mice were randomly divided into control and MCZ groups (10 mice each).
Jialu Bao   +4 more
doaj   +1 more source

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

open access: yes, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue   +5 more
core   +1 more source

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis [PDF]

open access: yes, 2016
During late gestation, villi extend into the intestinal lumen to dramatically increase the surface area of the intestinal epithelium, preparing the gut for the neonatal diet.
Bonder, Edward M.   +13 more
core   +1 more source

Mutant mitochondrial elongation factor G1 and combined oxidative phosphorylation deficiency [PDF]

open access: yes, 2004
Although most components of the mitochondrial translation apparatus are encoded by nuclear genes, all known molecular defects associated with impaired mitochondrial translation are due to mutations in mitochondrial DNA.
Antonicka, H   +10 more
core   +4 more sources

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes [PDF]

open access: yes, 2017
Thioredoxin 1 (Trx1) is a 12-kDa oxidoreductase that catalyzes thiol-disulfide exchange reactions to reduce proteins with disulfide bonds. As such, Trx1 helps protect the heart against stresses, such as ischemia and pressure overload.
Bhat, Santosh   +16 more
core   +1 more source

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

open access: yesCell Reports, 2018
Summary: Transitioning from a metabolically quiescent naive B cell to an antibody-secreting plasmablast requires division-dependent cellular differentiation.
Madeline J. Price   +3 more
doaj   +1 more source

Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]

open access: yes, 2017
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle   +13 more
core   +2 more sources

MicroRNA‐661 modulates redox and metabolic homeostasis in colon cancer

open access: yesMolecular Oncology, 2017
Cancer cell survival and metastasis are dependent on metabolic reprogramming that is capable of increasing resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression.
Marta Gómez de Cedrón   +8 more
doaj   +1 more source

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