Results 201 to 210 of about 350,577 (307)

Nitric oxide: Protein tyrosine phosphorylation and protein S-nitrosylation in cancer

, 2015
Arnold Stern, P Da Costa, HugoP Monteiro, Adriana Karla Cardoso Amorim Reis   +3 more
openalex   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

ENO1 Knockdown Impedes Tumour Progression and Promotes Oxidative Phosphorylation in Cutaneous Squamous Cell Carcinoma. [PDF]

Acta Derm Venereol
Song L, Ma S, Wang S, Zhang X, Fan W, Wang N, Feng S, Duan Q, Bai R, Zheng Y.   +9 more
europepmc   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Gut Microbe-Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation. [PDF]

Adv Sci (Weinh)
HuangFu N, Zhu X, Tang Z, Wang L, Zhang K, Li D, Ji J, Cui J, Guo Z, Luo J, Gao X.   +10 more
europepmc   +1 more source

Phosphorylation of a novel STK substrate SstP1 links SUF Fe-S cluster biogenesis to oxidative stress resistance and virulence in Streptococcus suis

Shuying Ren, Hang Yin, Yiming Wang, Ru Yan, Xiaoyu Jia, Zhiwei Li, Yuqing Li, Yutong Tian, Lianci Peng, Juan Li, Rendong Fang   +10 more
openalex   +1 more source

3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation [PDF]

Yijia Shi, Xiao Tong, Yali Weng, Ya Xiao, Jintao Wu, Jing Wang, Wen‐Min Wang, Ming Yan, Ming Yan, Zehan Li, Jinhua Yu   +10 more
openalex   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source

Construction and validation of an oxidative phosphorylation-related gene signature in lung squamous cell carcinoma patients. [PDF]

Lung Cancer Manag
Dai N, Fang C, Gu Y, Wang B, Feng W, Pan K, Jiang W, Li G, Ma H.   +8 more
europepmc   +1 more source

Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis

Ruobing Zhang, Wenjing Yang, Kai Li, Xiaolong Zhang, Jie Liu, Lin Ai   +5 more
openalex   +1 more source