Results 81 to 90 of about 309,295 (244)
Coupling of Phosphorylation and Oxidation Processes [PDF]
C. E. H. Bawn, W. E. Garner
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In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu+10 more
wiley +1 more source
A POLYNUCLEOTIDE COENZYME OF OXIDATIVE PHOSPHORYLATION II
Gifford B. Pinchot
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This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao+21 more
wiley +1 more source
OXIDATIVE PHOSPHORYLATION IN ACETOBACTER SUBOXYDANS
Leiv Klungsoüyr+2 more
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The Efficiency of Oxidative Phosphorylation by Normal and Leukemic Human Leukocytes [PDF]
Virginia E. Davis+2 more
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These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang+9 more
wiley +1 more source
Oxidative Phosphorylation in Uncoupled Mitochondria. [PDF]
Brunetta HS, Mori MA, Bartelt A.
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The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu+20 more
wiley +1 more source