Results 121 to 130 of about 360,858 (306)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Oxidative stability of wild-type and mutant proteins.

, 2013
The relative activity (%) was determined and compared with the activity without the addition of H2O2. A: Oxidative stability of the one-site mutant enzymes. B: Oxidative stability of eight five-site mutant enzymes.
Guocheng Du (390526), Haiquan Yang (390522), Jianghua Li (390525), Long Liu (390523), Jian Chen (15340), Hyun-dong Shin (390524)   +5 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of squalene absorption on oxidative stability of highly crosslinked UHMWPE stabilized with natural polyphenols

, 2014
The uptake of synovial lipids into ultra high molecular weight polyethylene (UHMWPE) has been recently related with the in vivo and ex vivo oxidation of irradiated and remelted UHMWPE.
Liu, Xincai, Shen, Jie, Fu, Jun
core  

Sustainable Valorization of Crickets: Optimized Low-Pressure Supercritical CO₂ Extraction and the Oil’s Properties and Stability

Foods
As part of the green valorization of crickets, cricket oil was extracted using supercritical CO2 at temperatures of 40–60 °C, pressures of 175–225 bar, and extraction times of 1–5 h to evaluate oil yield and physicochemical properties.
Dolaya Sadubsarn, Rattana Muangrat
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Effect of Long-Term Storage Temperature on the Quality of Extra-Virgin Olive Oil (Coratina cv.): A Multivariate Discriminant Approach

Antioxidants
Kinetic evolution of quality parameters in 21 extra-virgin olive oils (EVOOs) from Coratina cultivar was evaluated during 18 months of dark storage at room temperature (RT) and 4 °C (LT).
Pasquale Crupi, Maria Lisa Clodoveo, Addolorata Desantis, Roberta Zupo, Filomena Corbo   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Effects of Solvent-Salt Charge-Transfer Complexes on Oxidative Stability of Li-Ion Battery Electrolytes

, 2018
Electrochemical stability windows of electrolytes largely determine the limitations of operating regimes and energy density of Li-ion batteries but the controlling degradation mechanisms are difficult to characterize and remain poorly understood.
Jonathan P., Mailoa, Boris V., Merinov, Jeffrey C., Grossman, Francesco, Faglioni, Eric, Fadel, William A., Goddard III, Boris, Kozinsky, Nicola, Molinari, Georgy, Samsonidze   +8 more
core   +1 more source