Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
p-Cresol Sulfate Caused Behavior Disorders and Neurodegeneration in Mice with Unilateral Nephrectomy Involving Oxidative Stress and Neuroinflammation [PDF]
, 2020 Chiao‐Yin Sun +8 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Magnetically tuned thermoelectric properties of metal-oxides: a review
Materials Research ExpressIn recent years, research on thermoelectric materials has garnered considerable attention, owing to their potential to offer efficient and environmentally friendly energy solutions.
Divya Prakash Dubey +1 more
doaj +1 more source
Difference in High-Temperature Tribological Performance of Oxide/Ag-MoS2-Based Composites
LubricantsMoS2 has excellent vacuum lubricating performance. However, it is prone to be oxidized in a high-temperature atmospheric environment, leading to the deterioration of its lubricating performance and even serious space accidents.
Yufei Wang +5 more
doaj +1 more source
Colossal Effects in Transition Metal Oxides Caused by Intrinsic Inhomogeneities [PDF]
, 2001 Jan Burgy +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Expression of Constitutive and Inducible Nitric Oxide Synthases in the Vascular Wall of Young and Aging Rats [PDF]
, 1998 M.R. Cernadas +14 more
openalex +1 more source
The First Step in Solar Hydrogen Production: Development of a Solar Thermal Reactor for the Reduction of Metal Oxide Particles [PDF]
, 2013 A solar thermal reactor has been designed to experimentally investigate promising paths for reducing metal oxide particles to reduced oxidation states (e.g. Fe2O3 to Fe3O4) utilizing concentrated solar energy.
Fosheim, Jesse, Schrader, Andrew
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source