Results 61 to 70 of about 389,522 (309)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Copper catalyzed one-pot synthesis of beta-ketophosphine oxides from ketones and H-phosphine oxides
, 2017 A facile and efficient copper catalyzed one-pot method has been developed for the formation of beta-ketophosphine oxides from ketones and H-phosphine oxides under air at room temperature, in which vinylhydrazinedicarboxylate was formed as the key ...
Ji, JX +10 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Possibilities for carbon sequestration in Irish forests. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2000 Ireland has a rapidly expanding forest estate which covers some 9/ of the land area. It is government policy to increase this to 17/ by the year 2030. Preliminary studies suggest that forestry activities have the potential to contribute significantly to ...
Byrne K.A., Perks M.
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
A General [3 + 2 + 1] Annulation Strategy for the Preparation of Pyridine N-Oxides
, 2016 Stabilized ketone, aldehyde, and ester enolates react with vinamidinium hexafluorophosphate salts and hydroxylamine hydrochloride to give access to the corresponding pyridine N-oxides.
Ian W. Davies (1436695) +2 more
core +1 more source
, 2013 Detailed kinetic and computational investigation of the enantio- and diastereoselective allylation of aldehydes with allyltrichlorosilanes, employing the pyridine N-oxides METHOX and QUINOX as chiral organocatalysts, indicate that the reaction can ...
Mark Bell (2435983) +8 more
core +4 more sources
Electrically induced cancellation and inversion of piezoelectricity in ferroelectric Hf0.5Zr0.5O2
Nature CommunicationsHfO2-based thin films hold huge promise for integrated devices as they show full compatibility with semiconductor technologies and robust ferroelectric properties at nanometer scale.
Haidong Lu +10 more
doaj +1 more source