Results 61 to 70 of about 149,372 (269)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Study of hyperfine interactions in spinel cobalt ferrite CoFe2O4 doped with Hf, Lu, and Yb using Mössbauer spectroscopy and perturbed γ-γ angular correlation

open access: yesКонденсированные среды и межфазные границы
We studied hyperfine interactions (HFI) in spinel cobalt ferrite (ferrospinel) CoFe2O4 doped with Lu, Yb, and Hf (1 wt. %) by Mössbauer spectroscopy (MS) on 57Fe nuclei.
Viktor M. Vakhtel   +7 more
doaj   +1 more source

Cyclic Oxidation and Hot Corrosion Behavior of Nickel–Iron-Based Superalloy

open access: yesHigh Temperature Materials and Processes, 2018
The high temperature oxidation and hot corrosion behavior of nickel–iron-based superalloy are studied at 900 ° and 1000 °C. The significant role of alloying elements with respect to the exposed medium is studied in detail.
Chellaganesh D.   +3 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Reconfigurable nanoionic and photoionic material and device platforms

open access: yesAdvances in Physics: X
Nanoionic and photoionic reconfigurable oxides and chalcogenide semiconductors are emerging material platforms for field-based, non-volatile control of electrons and photons in nanoscale optoelectronic device architectures.
Ahmed H. Elfarash, Behrad Gholipour
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Monitoring and reporting carbon stocks and fluxes in Dutch forests. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2000
Global forests play an important role in the global carbon cycle. At this moment they absorb about 25/ of the emission of carbon dioxide. This aspect has initiated research into the possibilities of enhancing and maintaining this role of global forests ...
Nabuurs G.J., Dolman H., Mohren F.
doaj  

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