Traffic air pollution and oxidized LDL. [PDF]
PLoS ONE, 2011 BackgroundEpidemiologic studies indirectly suggest that air pollution accelerates atherosclerosis. We hypothesized that individual exposure to particulate matter (PM) derived from fossil fuel would correlate with plasma concentrations of oxidized low ...
Lotte Jacobs +6 more
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Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL. [PDF]
PLoS ONE, 2016 Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and is associated with type 2 diabetes. Here, we investigated whether the endoplasmic reticulum (ER)
Valérie Plaisance +14 more
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Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL.
Journal of Lipid Research, 1994 Low density lipoprotein that was oxidized by activated human monocytes was analyzed to determine the identity of oxidized fatty acids present and the conditions required for their formation.
V A Folcik, M K Cathcart
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Oxidized LDL is stable in human serum under extended thawed-state conditions ranging from −20 °C to room temperature [PDF]
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023 Introduction: Oxidized LDL (oxLDL) is formed by the spontaneous reaction between aldehyde byproducts of lipid peroxidation and lysine residues of apolipoprotein B within LDL.
Nilojan Jehanathan +5 more
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Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress. [PDF]
PLoS ONE, 2010 Oxidized low-density lipoproteins (oxLDL) and oxLDL-containing immune complexes (oxLDL-IC) contribute to formation of lipid-laden macrophages (foam cells).
Mohammed M Al Gadban +9 more
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Frontiers in Veterinary Science, 2015 Oxidized low-density lipoprotein (LDL) is thought to play an important role in the inflammatory response associated with human obesity. The purpose of this preliminary study was to determine oxidized LDL concentrations in healthy dogs and cats, and to ...
Nobuko eMori, Toshiro eArai
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Involvement of Low‐Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background Recently, we and others have reported a causal role for oxidized lipids in the pathogenesis of pulmonary hypertension (PH). However, the role of low‐density lipoprotein receptor (LDL‐R) in PH is not known.
Soban Umar +15 more
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Oxidised LDL and Serum Paraoxanase Activity in Ischemic Stroke Patients: A Case Control Study [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Oxidative stress by producing lipid peroxidation products like oxidised Low Density Lipoprotein (LDL) acts as independent risk factor in ischemic stroke.
Poornima Bijumon +2 more
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Antioxidants, 2021 Oxidized low-density lipoproteins play an important role in tissue pathology. In this study, we report a sensitive novel enzyme-linked immunosorbent assay for the detection of malondialdehyde-modified low-density lipoprotein (MDA-LDL), a key component of
Samata S. Pandey +11 more
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Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model. [PDF]
PLoS ONE, 2012 BACKGROUND: Atherosclerosis starts by lipid accumulation in the arterial intima and progresses into a chronic vascular inflammatory disease. A major atherogenic process is the formation of lipid-loaded macrophages in which a breakdown of the endolysomal ...
Luis M B B Estronca +7 more
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