Results 11 to 20 of about 75,484 (307)
Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress. [PDF]
PLoS ONE, 2010 Oxidized low-density lipoproteins (oxLDL) and oxLDL-containing immune complexes (oxLDL-IC) contribute to formation of lipid-laden macrophages (foam cells).
Mohammed M Al Gadban +9 more
doaj +4 more sources
Traffic air pollution and oxidized LDL. [PDF]
PLoS ONE, 2011 BackgroundEpidemiologic studies indirectly suggest that air pollution accelerates atherosclerosis. We hypothesized that individual exposure to particulate matter (PM) derived from fossil fuel would correlate with plasma concentrations of oxidized low ...
Lotte Jacobs +6 more
doaj +6 more sources
Journal of Lipid Research, 1998 Monocytes can be activated by incubation with opsonized zymosan (Zop), and under these conditions can oxidize low density lipoprotein (LDL). We have characterized the biochemical changes in the lipoprotein after this oxidation.
Xiaoyan Xing +2 more
doaj +3 more sources
Oxidized LDLs as Signaling Molecules [PDF]
Antioxidants, 2021 Levels of oxidized low-density lipoproteins (oxLDLs) are usually low in vivo but can increase whenever the balance between formation and scavenging of free radicals is impaired. Under normal conditions, uptake and degradation represent the physiological cellular response to oxLDL exposure.
Zingg J. -M., Vlad A., Ricciarelli R.
openaire +4 more sources
Oxidized LDL and antioxidants [PDF]
Clinical Cardiology, 1993 Several studies have shown that the oxidative modification of low-density lipoprotein (LDL) may promote fatty-streak formation, the early lesion of atherosclerosis. Epidemiologic data suggest that decreased levels of micronutrient antioxidants are associated with an increased frequency of cardiovascular disease.
I, Jialal, C J, Fuller
openaire +2 more sources
Oxidized LDL and the Metabolic Syndrome [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 The metabolic syndrome is a common and complex disorder combining obesity, dyslipidemia, hypertension and insulin resistance. It is associated with a high cardiovascular risk that can only partially be explained by its components. There is evidence that low-grade inflammation and high oxidative stress add to this risk.
Paul, Holvoet +3 more
openaire +2 more sources
Mechanisms of enhanced macrophage apoE secretion by oxidized LDL
Journal of Lipid Research, 1997 Previous studies have demonstrated that atherosclerotic lesions contain apoE synthesized primarily by macrophages. As oxidized LDL has been implicated in the development of atherosclerosis, its effect on macrophage apoE synthesis and secretion was ...
A A Cader +3 more
doaj +1 more source
Antioxidants, 2021 Oxidized low-density lipoproteins play an important role in tissue pathology. In this study, we report a sensitive novel enzyme-linked immunosorbent assay for the detection of malondialdehyde-modified low-density lipoprotein (MDA-LDL), a key component of
Samata S. Pandey +11 more
doaj +1 more source
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
, 2006 Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Siess, Wolfgang
core +1 more source
Journal of Lipid Research, 2000 Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells.
Baljinder S. Dhaliwal +1 more
doaj +1 more source