Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins
Journal of Lipid Research, 2006 Oxidized cholesterol is present in significant quantities in the typical Western diet. When ingested, oxidized cholesterol is absorbed by the small intestine and incorporated into both chylomicrons and LDL, resulting in LDL that is more susceptible to ...
Ilona Staprans +4 more
doaj
In Vivo Uptake of Radiolabeled MDA2, an Oxidation-Specific Monoclonal Antibody, Provides an Accurate Measure of Atherosclerotic Lesions Rich in Oxidized LDL and Is Highly Sensitive to Their Regression [PDF]
, 2000 Sotirios Tsimikas +3 more
openalex +1 more source
Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Food Safety and Health, EarlyView.Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar +5 more
wiley +1 more source
Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration. [PDF]
Mediators Inflamm, 2023 Chandrasekar B +3 more
europepmc +1 more source
Oxidized Cholesterol in the Diet Accelerates the Development of Atherosclerosis in LDL Receptor– and Apolipoprotein E–Deficient Mice [PDF]
, 2000 Ilona Staprãns +4 more
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Food Safety and Health, EarlyView.Curcuma aromatica rhizome ethanolic extracts (400 mg/kg) showed hypoglycemic and hypolipidemic activities in alloxan‐induced diabetic rats, comparable to standard drugs in reducing blood glucose levels. The extracts reduced serum cholesterol and triglycerides, increased HDL levels, and prevented weight loss.
Salma Khadka +6 more
wiley +1 more source
Journal of Lipid Research, 2000 Although numerous studies have investigated the relationship between cholesteryl ester transfer protein (CETP) and high density lipoprotein (HDL) remodeling, the relationship between CETP and low density lipoproteins (LDL) is still not fully understood ...
Masahiro Sugano +4 more
doaj
Retraction: Oxidized LDL causes endothelial apoptosis by inhibiting mitochondrial fusion and mitochondria autophagy. [PDF]
Front Cell Dev Biol, 2022 Frontiers Editorial Office.
europepmc +1 more source
Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors [PDF]
, 2000 Kristin L. Gillotte +3 more
openalex +1 more source
Glia, EarlyView.Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather +4 more
wiley +1 more source