Results 171 to 180 of about 75,484 (307)

Oxidized LDL and oxidative injuries

Pathophysiology, 1998
Sampath Parthasarathy, Nalini Santanam, Nathalie Augé   +2 more
openaire   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Oxidized LDL Induces Pro-Inflammatory Transcriptomic and Epigenomic Responses in Human CD4⁺ T Cells. [PDF]

FASEB J
Brown TA, Chalisey A, Jiang J, O'Callaghan CA.   +3 more
europepmc   +1 more source

The effect of myeloperoxidase-oxidized LDL on THP-1 macrophage polarization and repolarization. [PDF]

Innate Immun, 2022
Bazzi S, Frangie C, Azar E, Daher J.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Bridging the gap between CVD and COVID-19: the oxidized LDL hypothesis. [PDF]

Front Med (Lausanne)
Daher J.
europepmc   +1 more source

Oxidized LDL is stable in human serum under extended thawed-state conditions ranging from -20 °C to room temperature. [PDF]

J Mass Spectrom Adv Clin Lab, 2023
Jehanathan N, Kapuruge EP, Rogers SP, Williams S, Chung Y, Borges CR.   +5 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Clinical Association of Haptoglobin with Oxidized LDL in Obese Patients with Type 2 Diabetes Mellitus. [PDF]

Nutrients
Bakillah A, Al Subaiee M, Obeid KK, Soliman AF, Al Otaibi A, Mubarak SAS, Al Mihmadi YA, Bashir SF, Al Arab M, Al Hussaini A, Al Qarni AA.   +10 more
europepmc   +1 more source

Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration. [PDF]

Mediators Inflamm, 2023
Chandrasekar B, Mummidi S, DeMarco VG, Higashi Y.   +3 more
europepmc   +1 more source