Results 11 to 20 of about 78,045 (288)

Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1

Journal of Lipid Research, 2000
Apolipoprotein A-I (apoA-I) and an apoA-I peptide mimetic removed seeding molecules from human low density lipoprotein (LDL) and rendered the LDL resistant to oxidation by human artery wall cells.
Mohamad Navab, Susan Y. Hama, C. Justin Cooke, G.M. Anantharamaiah, Manjula Chaddha, Linda Jin, Ganesamoorthy Subbanagounder, Kym F. Faull, Srinivasa T. Reddy, Norman E. Miller, Alan M. Fogelman   +10 more
doaj   +1 more source

Oxidised LDL and Serum Paraoxanase Activity in Ischemic Stroke Patients: A Case Control Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Oxidative stress by producing lipid peroxidation products like oxidised Low Density Lipoprotein (LDL) acts as independent risk factor in ischemic stroke.
Poornima Bijumon, Geetha Ananthashenoyi, Thomas Iype   +2 more
doaj   +1 more source

Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study [PDF]

, 2015
Background: Olive oil (OO) consumption is associated with cardiovascular disease prevention because of both its oleic acid and phenolic contents. The capacity of OO phenolics to protect against low-density lipoprotein (LDL) oxidation is the basis for a ...
Altman, American Diabetes Association, Ayse Karadag, Benzie, Brookes, Carrasco-Pancorbo, Charles, Coon, Covas, Covas, Dakna, Delles, Emilie Combet, Farràs, Favati, Fitó, Fliser, Friedewald, Harald Mischak, Hollman, Julian, Justina Siwy, Kontogianni, Kroke, Lawes, Lee, Levi, Lopez-Miranda, Maahs, Maria E Figueira, Maria R Bronze, Martín-Peláez, Mischak, Mullen, Owen, Reaven, Rossi Sa, Sandra Silva, Snell-Bergeon, Sofi, Theodorescu, Tripoli, Tunstall-Pedoe, Urpi-Sarda, Vlassopoulos, Vlassopoulos, William Mullen, Zimmerli   +47 more
core   +1 more source

Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3

Journal of Lipid Research, 2000
Treatment of human artery wall cells with apolipoprotein A-I (apoA-I), but not apoA-II, with an apoA-I peptide mimetic, or with high density lipoprotein (HDL), or paraoxonase, rendered the cells unable to oxidize low density lipoprotein (LDL).
Mohamad Navab, Susan Y. Hama, G.M. Anantharamaiah, Kholood Hassan, Greg P. Hough, Andrew D. Watson, Srinivasa T. Reddy, Alex Sevanian, Gregg C. Fonarow, Alan M. Fogelman   +9 more
doaj   +1 more source

Mechanisms of enhanced macrophage apoE secretion by oxidized LDL

Journal of Lipid Research, 1997
Previous studies have demonstrated that atherosclerotic lesions contain apoE synthesized primarily by macrophages. As oxidized LDL has been implicated in the development of atherosclerosis, its effect on macrophage apoE synthesis and secretion was ...
A A Cader, F M Steinberg, T Mazzone, A Chait   +3 more
doaj   +1 more source

A Novel Immunoassay for Malondialdehyde-Conjugated Low-Density Lipoprotein Measures Dynamic Changes in the Blood of Patients Undergoing Coronary Artery Bypass Graft Surgery

Antioxidants, 2021
Oxidized low-density lipoproteins play an important role in tissue pathology. In this study, we report a sensitive novel enzyme-linked immunosorbent assay for the detection of malondialdehyde-modified low-density lipoprotein (MDA-LDL), a key component of
Samata S. Pandey, Adam Hartley, Mikhail Caga-Anan, Tareq Ammari, Ameer Hamid Ahmed Khan, Bao Anh Vu Nguyen, Chiari Kojima, Jon Anderson, Steven Lynham, Michael Johns, Dorian O. Haskard, Ramzi Y. Khamis   +11 more
doaj   +1 more source

Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]

, 2017
Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto, Loffredo, Lorenzo, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +4 more
core   +1 more source

Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally

Journal of Lipid Research, 2000
Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells.
Baljinder S. Dhaliwal, Urs P. Steinbrecher   +1 more
doaj   +1 more source

Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress. [PDF]

PLoS ONE, 2010
Oxidized low-density lipoproteins (oxLDL) and oxLDL-containing immune complexes (oxLDL-IC) contribute to formation of lipid-laden macrophages (foam cells).
Mohammed M Al Gadban, Kent J Smith, Farzan Soodavar, Christabelle Piansay, Charlyne Chassereau, Waleed O Twal, Richard L Klein, Gabriel Virella, Maria F Lopes-Virella, Samar M Hammad   +9 more
doaj   +1 more source

Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes [PDF]

, 2014
This work was funded by the Chief Scientists Office of the Scottish Government by a joint grant to the University of the Highland and Islands, Grampian Health Board, Biomathematics and Statistics Scotland and the Rowett Institute of Nutrition and Health,
Abraham, Prakash, De Roos, Baukje, Holtrop, Grietje, Johnstone, Alexandra M., Lobley, Gerald E., MacRury, Sandra M., McGeoch, Susan C., Megson, Ian L., O'Kennedy, Niamh, Pearson, Donald W. M., Zhang, Xuguang   +10 more
core   +1 more source