Results 11 to 20 of about 516,802 (337)
The Dynamics of Oxidized LDL during Atherogenesis [PDF]
Journal of Lipids, 2011 Accumulating evidence indicates that oxidized low-density lipoprotein (OxLDL) is a useful marker for cardiovascular disease. The uptake of OxLDL by scavenger receptors leads to the accumulation of cholesterol within the foam cells of atherosclerotic ...
H. Itabe, T. Obama, R. Kato
semanticscholar +4 more sources
Mechanisms of Oxidized LDL-Mediated Endothelial Dysfunction and Its Consequences for the Development of Atherosclerosis. [PDF]
Front Cardiovasc Med, 2022 Atherosclerosis is an immuno-metabolic disease involving chronic inflammation, oxidative stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting numerous modifications including the change of the size, density, and ...
Jiang H +7 more
europepmc +2 more sources
Journal of Lipid Research, 1998 Monocytes can be activated by incubation with opsonized zymosan (Zop), and under these conditions can oxidize low density lipoprotein (LDL). We have characterized the biochemical changes in the lipoprotein after this oxidation.
Xiaoyan Xing +2 more
doaj +4 more sources
Oxidized LDLs as Signaling Molecules [PDF]
Antioxidants, 2021 Levels of oxidized low-density lipoproteins (oxLDLs) are usually low in vivo but can increase whenever the balance between formation and scavenging of free radicals is impaired. Under normal conditions, uptake and degradation represent the physiological cellular response to oxLDL exposure.
Zingg J. -M., Vlad A., Ricciarelli R.
openaire +5 more sources
Oxidized LDL and antioxidants [PDF]
Clinical Cardiology, 1993 Several studies have shown that the oxidative modification of low-density lipoprotein (LDL) may promote fatty-streak formation, the early lesion of atherosclerosis. Epidemiologic data suggest that decreased levels of micronutrient antioxidants are associated with an increased frequency of cardiovascular disease.
Ishwarlal Jialal, Cindy J. Fuller
openaire +3 more sources
Oxidized LDL-anti-oxidized LDL immune complexes and diabetic nephropathy [PDF]
Diabetologia, 2002 Oxidized LDL is immunogenic and immune complexes formed by oxidized LDL and corresponding antibodies are pro-atherogenic and pro-inflammatory. Considering that macroalbuminuria is a risk factor for coronary heart disease and that common pathogenic factors for atherosclerosis and glomerulosclerosis exist, our aim was to determine whether the amount and ...
D Zheng +4 more
openaire +3 more sources
Oxidized LDL and the Metabolic Syndrome [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 The metabolic syndrome is a common and complex disorder combining obesity, dyslipidemia, hypertension and insulin resistance. It is associated with a high cardiovascular risk that can only partially be explained by its components. There is evidence that low-grade inflammation and high oxidative stress add to this risk.
Russell P. Tracy +3 more
openaire +3 more sources
Antioxidants, 2022 We aimed to investigate if major vascular surgery induces LDL oxidation, and whether circulating antibodies against malondialdehyde-modified LDL (MDA-LDL) alter dynamically in this setting.
Adam Hartley +12 more
doaj +1 more source
Mediators of Inflammation, 2013 We studied the influence of PON1 on metabolic alterations induced by oxidized LDL when incubated with endothelial cells. HUVEC cells were incubated with native LDL, oxidized LDL, oxidized LDL plus HDL from wild type mice, and oxidized LDL plus HDL from ...
Anabel García-Heredia +9 more
doaj +1 more source
Atheroprotective Effect of Oleoylethanolamide (OEA) Targeting Oxidized LDL
PLoS ONE, 2014 Dietary fat-derived lipid oleoylethanolamide (OEA) has shown to modulate lipid metabolism through a peroxisome proliferator-activated receptor-alpha (PPAR-α)-mediated mechanism. In our study, we further demonstrated that OEA, as an atheroprotective agent,
Angran Fan +9 more
semanticscholar +1 more source