Results 31 to 40 of about 89,126 (347)

Oxidized LDL induces alternative macrophage phenotype through activation of CD36 and PAFR [PDF]

, 2013
OxLDL is recognized by macrophage scavenger receptors, including CD36; we have recently found that Platelet-Activating Factor Receptor (PAFR) is also involved.
Ferracini, M., Gidlund, M., Jancar, S., Koga, M.M., Pecenin, M., Rios, F.J.   +5 more
core   +3 more sources

Identification of transition bias in oxidized low density lipoprotein receptor 1 gene in buffalo [PDF]

Veterinary World, 2014
Aim: Though transition bias has been previously demonstrated in cattle, however, there has not been any study that has explored transition bias in buffalo nuclear genome. The aim of the present study was to evaluate the nucleotide substitution pattern in
N. Shabir, Chetan V. Jawale, Naveed A. Chikan, C. D. Bhong, D. N. Rank , C. G. Joshi   +5 more
doaj   +1 more source

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages

Journal of Lipid Research, 2006
Oxidized low density lipoprotein (OxLDL) is immunogenic and induces autoimmune responses in humans. OxLDL antibodies are predominantly of the proinflammatory IgG1 and IgG3 isotypes. We tested the capacity of immune complexes prepared with copper-oxidized
Antonio F. Saad, Gabriel Virella, Charlyne Chassereau, Robert J. Boackle, Maria F. Lopes-Virella   +4 more
doaj   +1 more source

Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study [PDF]

, 2015
Background: Olive oil (OO) consumption is associated with cardiovascular disease prevention because of both its oleic acid and phenolic contents. The capacity of OO phenolics to protect against low-density lipoprotein (LDL) oxidation is the basis for a ...
Altman, American Diabetes Association, Ayse Karadag, Benzie, Brookes, Carrasco-Pancorbo, Charles, Coon, Covas, Covas, Dakna, Delles, Emilie Combet, Farràs, Favati, Fitó, Fliser, Friedewald, Harald Mischak, Hollman, Julian, Justina Siwy, Kontogianni, Kroke, Lawes, Lee, Levi, Lopez-Miranda, Maahs, Maria E Figueira, Maria R Bronze, Martín-Peláez, Mischak, Mullen, Owen, Reaven, Rossi Sa, Sandra Silva, Snell-Bergeon, Sofi, Theodorescu, Tripoli, Tunstall-Pedoe, Urpi-Sarda, Vlassopoulos, Vlassopoulos, William Mullen, Zimmerli   +47 more
core   +1 more source

Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]

, 2019
Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde, De Bruyne, Sander, Delanghe, Joris, Delanghe, Sigurd, Speeckaert, Marijn, Van Biesen, Wim   +5 more
core   +1 more source

Highly oxidized low-density lipoprotein does not facilitate platelet aggregation

Journal of International Medical Research, 2020
Objective This study aimed to examine whether oxidized low-density lipoprotein (oxLDL) facilitates platelet aggregation, which is one cause for development of cardiovascular disease. Methods The susceptibility of platelets to aggregation was monitored by
Akari Miyazaki, Takeshi Uehara, Yoko Usami, Nau Ishimine, Mitsutoshi Sugano, Minoru Tozuka   +5 more
doaj   +1 more source

Role of pyruvate kinase M2 in oxidized LDL-induced macrophage foam cell formation and inflammation[S]

Journal of Lipid Research, 2020
Pyruvate kinase M2 (PKM2) links metabolic and inflammatory dysfunction in atherosclerotic coronary artery disease; however, its role in oxidized LDL (Ox-LDL)-induced macrophage foam cell formation and inflammation is unknown and therefore was studied. In
Amit Kumar, Priya Gupta, Minakshi Rana, Tulika Chandra, Madhu Dikshit, Manoj Kumar Barthwal   +5 more
doaj   +1 more source

Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial. [PDF]

, 2017
A single dose of the apolipoprotein (apo)A-I mimetic peptide D-4F rendered high-density lipoprotein (HDL) less inflammatory, motivating the first multiple-dose study. We aimed to assess safety/tolerability, pharmacokinetics, and pharmacodynamics of daily,
Bloedon, LeAnne T., Duffy, Danielle, Dunbar, Richard L., Fogelman, Alan M., Movva, Rajesh, Navab, Mohamad, Norris, Robert B., Rader, Daniel J.   +7 more
core   +2 more sources

Oxidized Low-density Lipoprotein and Atherosclerosis

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
Atherosclerosis is a chronic inflammatory disease characterized by lipid buildup and immune response dysregulation in the artery walls. One of the important participants is oxidized low-density lipoprotein (OxLDL), which is involved in both the ...
Ali M. A. Al-Kufaishi, Noor J. T. Al-Musawi   +1 more
doaj   +1 more source