The Role of Oxidized Low Density Lipoprotein in Atherogenesis [PDF]
An elevated level of low density lipoprotein (LDL) cholesterol constitutes a major risk factor for atherosclerotic disease. Although the precise mechanism(s) via which LDL promotes atherogenesis remains to be elucidated, the oxidative modification of LDL may be a crucial mechanism.
I, Jialal, S, Devaraj
openaire +2 more sources
Oxidized Low‐Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles
Background Activated vascular cells produce submicron prothrombotic and proinflammatory microparticle vesicles. Atherosclerotic plaques contain high levels of microparticles.
Julio F. Marchini +7 more
doaj +1 more source
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT +28 more
core +1 more source
Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. [PDF]
ObjectiveIn mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patients and whether 4F treatment improves
Boldrini, Beatrice +7 more
core +1 more source
Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]
The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A +5 more
core +1 more source
Supervised exercise training and increased physical activity to reduce cardiovascular disease risk in women with polycystic ovary syndrome: Study protocol for a randomized controlled feasibility trial [PDF]
Background: Polycystic ovary syndrome (PCOS) affects up to 20% of women and is characterised by higher amounts of visceral fat, obesity, insulin resistance, dyslipidemia and reproductive and cardiometabolic complications.
Broom, David +4 more
core +2 more sources
Plasma Level of Oxidized Low- Density Lipoprotein in Macroalbuminuric [PDF]
Accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy.
Manoochehr Nakhjavani +3 more
doaj +1 more source
The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD [PDF]
Objective The balance between coronary endothelial dysfunction and repair is influenced by many protective and deleterious factors circulating in the blood.
Ahmed, Nadeem +7 more
core +1 more source
Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Berliner JA +23 more
core +1 more source
Most studies of antibodies to oxidized LDL have been undertaken in patients with different diseases and cardiovascular risk factors. However, very few studies have researched the distribution and determining factors of antibodies to oxidized LDL in the ...
Francisco J. Tinahones +8 more
doaj +1 more source

