Results 271 to 280 of about 655,979 (316)

Oxidized phospholipids and lipoprotein(a): An update [PDF]

European Journal of Clinical Investigation, 2021
Over the past few years, there has been an undiminished interest in lipoprotein(a) [Lp(a)] and oxidized phospholipids (OxPLs), mainly carried on this lipoprotein. Elevated Lp(a) has been established as an independent causal risk factor for cardiovascular
A. Koutsogianni, E. Liberopoulos, Konstantinos Tellis, A. Tselepis   +3 more
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Oxidized phospholipids and lipoprotein‐associated phospholipase A2 (Lp‐PLA2) in atherosclerotic cardiovascular disease: An update

BioFactors, 2022
Inflammation and oxidative stress conditions lead to a variety of oxidative modifications of lipoprotein phospholipids implicated in the occurrence and development of atherosclerotic lesions.
Despoina Pantazi, Styliani Papadaki
exaly   +2 more sources

Oxidized phospholipids as novel mediators of neurodegeneration.

Trends in Neurosciences, 2022
Neurodegeneration drives the progression of many neurological diseases. Inflammation and oxidative stress occurring in the CNS promote lipid peroxidation, leading to the generation of oxidized phospholipids such as oxidized phosphatidylcholines (OxPCs ...
Yifei Dong, V. Yong
semanticscholar   +3 more sources

Oxidized phospholipids in cardiovascular disease

Nature Reviews Cardiology, 2023
Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma on apolipoprotein B (apoB)-containing lipoproteins. When initially conceptualized, OxPL-apoB measurement in plasma was expected to reflect the concentration of minimally oxidized ...
S. Tsimikas, J. Witztum
semanticscholar   +3 more sources

Phospholipid oxidation in emulsions

Lipids, 1970
AbstractThe autoxidation of purified phosphatidyl ethanolamine (PE) and phosphatidyl choline (PC), extracted from egg and soybean lipids, was followed by oxygen uptake measurements in emulsified systems. All emulsified phospholipid fractions had comparable activation energies.
G A, Corliss, L R, Dugan
openaire   +2 more sources

Oxidized phospholipids, isolevuglandins, and atherosclerosis

Molecular Nutrition & Food Research, 2005
Autoxidation of polyunsaturated phosphatidylcholines (PCs) generates isolevuglandins (isoLGs) through rearrangements of isoprostanoid endoperoxides. Within seconds, isoLGs are sequestered by covalent adduction with proteins. Murine plasma isoLG-protein levels increased at least 2.5-fold in response to inflammation.
Wujuan, Zhang, Robert G, Salomon
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Oxidized phospholipids: Biomarker for cardiovascular diseases [PDF]

International Journal of Biochemistry and Cell Biology, 2009
Biologically active oxidized phospholipids can initiate and modulate many of the cellular events attributed to inflammation leading to atherosclerosis. Produced by enzymatic or non-enzymatic processes, these molecules interact with various cells via specific receptors and in general give rise to inflammatory signals. There is considerable evidence that
Mohammad Z, Ashraf, Niladri S, Kar, Eugene A, Podrez   +2 more
exaly   +3 more sources

Oxidized phospholipids and isoprostanes in atherosclerosis

Current Opinion in Lipidology, 1998
Lipid oxidation has been shown to be a prominent feature of atherosclerosis. The presence of isoprostanes and other lipid oxidation products has been clearly demonstrated in lesions. Furthermore, antibodies to oxidized phospholipids have been identified in animal and human models.
J L, Witztum, J A, Berliner
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Oxidized Phospholipids and Calcific Aortic Valvular Disease.

Journal of the American College of Cardiology
BACKGROUND Oxidized phospholipids (OxPLs) are carried by apolipoprotein B-100-containing lipoproteins (OxPL-apoB) including lipoprotein(a) (Lp[a]). Both OxPL-apoB and Lp(a) have been associated with calcific aortic valve disease (CAVD). OBJECTIVES This
H. Bhatia, Marc R. Dweck, Neil Craig, R. Capoulade, Philippe Pibarot, Patrick J. Trainor, S. Whelton, R. Rikhi, K. Lidani, Wendy S Post, Michael Y. Tsai, M. Criqui, Michael D. Shapiro, Matthew J. Budoff, Andrew P DeFilippis, G. Thanassoulis, S. Tsimikas   +16 more
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Bioactive phospholipid oxidation products

Free Radical Biology and Medicine, 2000
Oxidation of phospholipids results in chain-shortened fragments and oxygenated derivatives of polyunsaturated sn-2 fatty acyl residues, generating a myriad of phospholipid products. Certain oxidation products of phosphatidylcholine bind to and activate the human receptor for PAF, and these PAF-like lipids are potent, selective inflammatory mediators ...
G K, Marathe, K A, Harrison, R C, Murphy, S M, Prescott, G A, Zimmerman, T M, McIntyre   +5 more
openaire   +2 more sources