Results 141 to 150 of about 171,220 (334)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Selective Oxidation of α,β‐Unsaturated Alcohols With Lyophilisates of Bjerkandera adusta

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The biocatalytic aerobic production of (E)‐2‐allylic aldehydes from their corresponding alcohols using lyophilisates of the basidiomycetous fungus Bjerkandera adusta is reported. The addition of small amounts of organic solvents to the reaction media increased the reaction and substrate conversion rates, allowing for to produce (E)‐aldehydes ...
Letizia Calza   +4 more
wiley   +1 more source

Relationship between plasma xanthine oxidoreductase activity and left ventricular ejection fraction and hypertrophy among cardiac patients

open access: gold, 2017
Yuki Fujimura   +9 more
openalex   +2 more sources

Integrated In Vitro and In Silico Characterization of 5‐Hydroxyferulic Acid: Antioxidant, Anti‐Inflammatory, Anti‐Hemolytic, and Cytotoxic Potential

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT In the pursuit of novel antioxidant and anti‐inflammatory agents, we investigated 5‐hydroxyferulic acid (5‐OHFA), a hydroxylated derivative of the well‐known phenolic compound ferulic acid (FA). This study aimed to determine whether structural modification enhances the biological activity of FA.
Syrine Sakouhi   +5 more
wiley   +1 more source

State of the Art Technologies for High Yield Heterologous Expression and Production of Oxidoreductase Enzymes: Glucose Oxidase, Cellobiose Dehydrogenase, Horseradish Peroxidase, and Laccases in Yeasts P. pastoris and S. cerevisiae

open access: yesFermentation
Oxidoreductase (OXR) enzymes are in high demand for biocatalytic applications in the food industry and cosmetics (glucose oxidase (GOx) and cellobiose dehydrogenase (CDH)), bioremediations (horseradish peroxidase (HRP) and laccase (LAC)), and medicine ...
Milica Crnoglavac Popović   +2 more
doaj   +1 more source

A Robust Bioprocess for the Global Incorporation of Noncanonical Amino Acids in Auxotrophic Hosts Produces Labeled Proteins at the Gram Scale

open access: yesChemBioChem, EarlyView.
A robust bioprocess enables global incorporation of noncanonical amino acids in both shake flask and bioreactor cultures, producing gram‐per‐liter titers of efficiently labeled proteins. A versatile Escherichia coli BL21(DE3) auxotroph platform supports broad compatibility with various noncanonical amino acids and target proteins, facilitating flexible
Patrik Fladischer   +8 more
wiley   +1 more source

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