Results 151 to 160 of about 171,220 (334)

Proton‐Coupled Electron Transfer in Cytochrome c Oxidase: Heme a Controls the Protonation Dynamics of E286

open access: yesChemPhysChem, EarlyView.
Deprotonation of the glutamic acid 286 in cytochrome c oxidase from Cereibacter sphaeroides occurs 13 μs after photolysis of the CO ligand. The reaction is triggered by subsequent backward electron transfer from the heme a3 to heme a, which immediately precedes the deprotonation event.
Federico Baserga   +5 more
wiley   +1 more source

Regulation of P450 oxidoreductase by gonadotropins in rat ovary and its effect on estrogen production [PDF]

open access: gold, 2008
Yoshihiko Inaoka   +7 more
openalex   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang   +6 more
wiley   +1 more source

Stereochemistry of the dTDP-glucose oxidoreductase reaction.

open access: hybrid, 1977
Carl E. Snipes   +4 more
openalex   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

open access: yesESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori   +9 more
wiley   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis   +11 more
wiley   +1 more source

SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases

open access: gold, 2022
Ping Liu   +10 more
openalex   +1 more source

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