Superoxide activates ferroptosis through the Haber‐Weiss reaction and contributes to the development of age‐related macular degeneration. MnSOD‐depleted RPE cells are susceptible to blue light‐induced ferroptosis. MnSOD deficiency promotes Hsp70‐driven ubiquitin‐mediated degradation of GPX4.
Ying Huang+10 more
wiley +1 more source
PPDPF: Preventing kidney disease through NAD<sup>+</sup> regulation. [PDF]
Imai SI.
europepmc +1 more source
Thermodynamics of Enzyme-Catalyzed Reactions: Part 1. Oxidoreductases [PDF]
Robert N. Goldberg+4 more
openalex +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Transcriptome Analysis Revealed That Cell Wall Regulatory Pathways Are Involved in the Tolerance of <i>Pleurotus ostreatus</i> Mycelia to Different Heat Stresses. [PDF]
Hou L+8 more
europepmc +1 more source
Studies on the expression of NDH-H, a subunit of the NAD(P)H-plastoquinone-oxidoreductase of higher-plant chloroplasts [PDF]
Susanne Berger+3 more
openalex +1 more source
Diffuse large B‐cell lymphoma is a heterogeneous and aggressive pathology. MicroRNAs, deregulated in patient tumours and blood, are promising non‐invasive predictive biomarkers for this pathology. We identified the circulating miR‐200c/421/324 signature both predictive of response to R‐CHOP and correlated with PFS.
Giulia Regazzo+15 more
wiley +1 more source
Complex Interplay of Metabolic Substrates, Points of Entry into the Mitochondrial Electron Chain, and ROS Generation: A critical analysis of "Active control of mitochondrial network morphology by metabolism-driven redox state" by Singh et al. and studies replacing ETC components with yeast counterparts. [PDF]
Speijer D.
europepmc +1 more source
Proteomic analysis of Trichoderma harzianum secretome and their role in the biosynthesis of zinc/iron oxide nanoparticles. [PDF]
Gallo MB+4 more
europepmc +1 more source