Results 191 to 200 of about 90,447 (247)

Investigating the dual role of mitochondrial and nuclear genome variants in pediatric cardiomyopathies. [PDF]

open access: yesSci Rep
Temena MA   +8 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Activation of choleragen by thiol: protein disulfide oxidoreductase.

open access: hybrid, 1980
Joel Moss   +3 more
openalex   +1 more source

Humeroradial Synostosis: An Updated Classification and Differential Diagnosis Based on Genetic Aetiology

open access: yesClinical Genetics, EarlyView.
The proposed updated classification of humeroradial synostosis is based on the molecular pathways of the genes involved: (1) chondrogenesis and osteogenesis; (2) limb development and patterning; (3) genome regulation. Thus, pathologies belonging to the same molecular type may have overlapping clinical phenotypes, helping to structure the diagnostic ...
Fiona Leduc   +5 more
wiley   +1 more source

Large scale identification of pellicle and cell-free liquid phase associated proteins in <i>Bacillus amyloliquefaciens</i> L-17. [PDF]

open access: yesCurr Res Microb Sci
Ouidir T   +4 more
europepmc   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

open access: yesCell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng   +10 more
wiley   +1 more source

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