Results 71 to 80 of about 90,447 (247)

Real‐Time Detection of Reduced Nitroreductase with a Reversible Fluorescent Probe

Advanced Science, EarlyView.
The first reversible binding probe (rNTRp) is presented that selectively detects the nitroreductase enzyme's active, reduced form (red‐NTR) with a fluorescence turn‐on response. Contrary to the conventional reaction‐based probes known to date, which provide only static information on the accumulated enzyme activity at a given time, rNTRp allows ...
Sourav Sarkar, Anushree Shil, Yong Woong Jun, Yun Jae Yang, Ranran Cheng, Wenli Wu, Xuechen Li, Qiongzheng Hu, Kyo Han Ahn   +8 more
wiley   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Carbon Nanomaterials with SOD-like Activity: The Effect of the Ionic Strength

Molecules
Electrogenerated hydrophilic carbon (EHC) nanomaterials emerge as a highly attractive option for mimicking the activity of the superoxide dismutase enzyme (SOD) due to their exceptional water solubility and electron-transfer reversibility.
Andreia D. Veloso, Romeu A. Videira, Maria C. Oliveira   +2 more
doaj   +1 more source

Hexopyranoside: Cytochrome c Oxidoreductase from Agrobacterium tumefaciens [PDF]

, 1968
Jozef Van Beeumen, J. De Ley
openalex   +1 more source

Non‐Random Distribution of EMS‐Induced Mutations Reveals Preference for Open Chromatin and Expressed Genes in Rice

Advanced Science, EarlyView.
Mutagenesis is an effective method for generating genetic resources with a long history in breeding; however, the randomness of chemical‐induced mutations has not been systematically investigated. In this study, over 7 million SNPms are identified in an EMS‐induced population, revealing that these mutations are non‐randomly distributed and ...
Xue‐Feng Yao, Yanhong Liu, Zhiyong Li, Guo‐Qiang Jiang, Wensheng Wang, Hong Lu, Huihui Li, Zefu Lu, Chun‐Ming Liu   +8 more
wiley   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

Animal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad, Fahmida Tasnim Richi, Rabiul Hossain, Md. Arafat, Pair Ahmed Jiko, Nazim Uddin Emon, Sayed Al Hossain Rabbi, Tirtha Khastagir, Md. Hemayet Hossain, Safaet Alam   +9 more
wiley   +1 more source

Initial Velocity and Product Inhibition Studies on L-Iditol:NAD Oxidoreductase. [PDF]

, 1975
Ulla Christensen, Erik Tüchsen, Bjørn Andersen, Gustav Schroll, Otto Dahl, O. Buchardt, Gustav Schroll   +6 more
openalex   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang, Yufei Li, Lin Zhang, Zhaoqing Li, Keqin Lin, Kai Huang, Zhaoqing Yang, Shaohui Ma, Hao Sun, Xiaochao Zhang   +9 more
wiley   +1 more source

Purification and Properties of Reduced Ferredoxin: CO₂ Oxidoreductase from Clostridium pasteurianum, a Molybdenum Iron‐Sulfur‐Protein [PDF]

, 1978
Paul Scherer, Rudolf K. Thauer
openalex   +1 more source

Transformation of Steroids by Cell-free Preparations of Penicillium lilacinum NRRL 895. V. Properties of 20-Oxopregnane Side Chain Cleavage and 20(alpha+beta)-Oxidoreductase Activities. [PDF]

, 1974
Kjell Carlström, Gunnel Sievers, Jacques Simonet, Jostein Krane, A. Taticchi, Bengt Mannervik   +5 more
openalex   +1 more source