Results 101 to 110 of about 44,293 (292)

Pyruvate-Ferredoxin Oxidoreductase

open access: hybrid, 1971
Kosaku Uyeda, Jesse C. Rabinowitz
openalex   +2 more sources

Enzymatic Diagnostics of Soil Health of the European Part of Russia with Lead Contamination

open access: yesSoil Systems
Lead (Pb) is one of the most common environmental pollutants. Lead has an acute toxic effect on soil biotas and the enzymatic system of soils. The objective of this study is to carry out enzymatic diagnostics of soil health in the European part of Russia
Tatiana Minnikova   +5 more
doaj   +1 more source

Identification of Pyrrolizilactone Biosynthetic Gene Cluster with Unique Short‐Chain Dehydrogenase Gene for 3‐Methylproline Formation

open access: yesChemistryEurope, EarlyView.
A standalone enzyme, derived from the reductase domain of a polyketide synthase‐nonribosomal peptide synthetase hybrid enzyme, is identified as a pyrroline carboxylate reductase. This enzyme is involved in the biosynthesis of 3‐methylproline, an amino acid building block of a unique tricyclic pyrrolizidinone structure of a fungal metabolite ...
Naoki Kato   +6 more
wiley   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang   +6 more
wiley   +1 more source

NRF2 signalling in cytoprotection and metabolism

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami   +4 more
wiley   +1 more source

Oxidoreductases: Significance for Humans and Microorganism

open access: yes, 2021
Oxidoreductases consist of a large class of enzymes catalyzing the transfer of electrons from an electron donor (reductant) to an electron acceptor (oxidant) molecule. Since so many chemical and biochemical transformations comprise oxidation/reduction processes, it has long been an important goal in biotechnology to develop practical biocatalytic ...
openaire   +3 more sources

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin   +5 more
wiley   +1 more source

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