Results 111 to 120 of about 62,951 (328)

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl, We Fong Siah, Efstratios Karavasilis, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Foteini Christidi, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Endoplasmic reticulum (ER) Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition

Frontiers in Oncology, 2014
Endoplasmic reticulum (ER) chaperones and oxidoreductases are abundant enzymes that mediate the production of fully folded secretory and transmembrane proteins. Resisting the Golgi and plasma membrane-directed bulk flow, ER chaperones and oxidoreductases
Thomas eSimmen, Tomas eGutierrez
doaj   +1 more source

Soil Extracellular Enzymes from Brazilian Cerrado as Quality Bioindicators in Agricultural Areas in Goiás, Brazil

Fronteiras: Journal of Social, Technological and Environmental Science, 2016
The conversion of native Cerrado areas for the implementation of crops alters the physicochemical properties and biochemistry of soil. In this study we sought to understand the effect of seasonality and management used for planting sugarcane on the ...
Leciana de Menezes Sousa Zago, Rogério Nunes Oliveira, Anne Kethlen Gonçalves Bombonatto, Letícia Mikaelly de Oliveira Moreira, Erik Nelson de Paiva Melo, Samantha Salomão Caramori   +5 more
doaj   +1 more source

Sulphur(lone pair)…π interactions with FAD in flavoenzymes [PDF]

, 2018
The interactions of π-systems with lone-pairs of electrons are known and have been described in biological systems, involving lone-pairs derived from metals, metalloids, sulphur, oxygen and nitrogen.
Caracelli, Ignez, Sacco, Antonio Cesar S, Silva, Rui F. N., Tiekink, Edward R. T. *, Zukerman-Schpector, Julio   +4 more
core  

Low NAD(P)H:quinone oxidoreductase 1 activity is associated with increased risk of acute leukemia in adults [PDF]

, 2001
Martyn T. Smith, Yunxia Wang, Eleanor Kane, Sara Rollinson, Joseph L. Wiemels, Eve Roman, Philippa L. Roddam, Raymond A. Cartwright, Gareth J. Morgan   +8 more
openalex   +1 more source

NAD(P)H : quinone Oxidoreductase 1 Deficiency and Increased Susceptibility to 7,12-Dimethylbenz[a]-anthracene-Induced Carcinogenesis in Mouse Skin [PDF]

, 2001
Delwin J. Long, Rebekah L. Waikel, Xia Wang, Dennis R. Roop, Anil K. Jaiswal   +4 more
openalex   +1 more source

The iron‐sulfur clusters in the two related forms of mitochondrial NADH: ubiquinone oxidoreductase made by Neurospora crassa [PDF]

, 1991
D C Wang, Steven W. Meinhardt, U. Sackmann, Hanns Weiss, Tomo̧ko Ohnishi   +4 more
openalex   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH [PDF]

, 2013
To date, efforts to switch the cofactor specificity of oxidoreductases from nicotinamide adenine dinucleotide phosphate (NADPH) to nicotinamide adenine dinucleotide (NADH) have been made on a case-by- case basis with varying degrees of success.
Arnold, Frances H., Brinkmann-Chen, Sabine, Brustad, Eric M., Cahn, Jackson K. B., Flock, Tilman, McIntosh, John A., Meinhold, Peter, Snow, Christopher D., Zhang, Liang   +8 more
core   +1 more source

Density functional theory in transition-metal chemistry: a self-consistent Hubbard U approach

, 2006
Transition-metal centers are the active sites for many biological and inorganic chemical reactions. Notwithstanding this central importance, density-functional theory calculations based on generalized-gradient approximations often fail to describe ...
C. Rovira, Damian A. Scherlis, Heather J. Kulik, Hollas, Matteo Cococcioni, Nicola Marzari   +5 more
core   +1 more source