Results 131 to 140 of about 44,664 (289)

Natural Melanin From Silky Fowl (Gallus gallus domesticus Brisson): Characterization and Protection of Caco‐2 Cells From Oxidative Stress via the Akt/Nrf2 Pathway

open access: yesFood Frontiers, EarlyView.
(created with BioRender.com) ABSTRACT Silky fowl, a unique chicken breed, exhibits black skin, meat, and bones due to the presence of natural melanin pigments. In our study, melanin from silky fowl (MSF) was isolated using an enzymatic extraction procedure and identified as a unique natural antioxidant.
Chunhui Xu   +5 more
wiley   +1 more source

University proceedings. Volga region. Natural sciences

open access: yesИзвестия высших учебных заведений. Поволжский регион: Естественные науки
Background. For scientifically substantiated and effective application of new biocidal compounds as means of protecting industrial materials from biodamage, ecophysiological studies are necessary to assess their effect on destructor microorganisms.
A.Yu. Shishkin   +4 more
doaj   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao   +6 more
wiley   +1 more source

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

open access: yesiMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin   +7 more
wiley   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Ecophysiology of two mesophotic octocorals intended for restoration: Effects of light and temperature

open access: yesLimnology and Oceanography, EarlyView.
Abstract Light and temperature are driving forces that shape the evolution and physiology of mesophotic organisms. On the Mississippi‐Alabama continental shelf, octocorals dominate the mesophotic seascape and provide habitat for many fish and invertebrate species.
Kassidy Lange   +8 more
wiley   +1 more source

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