Results 161 to 170 of about 43,837 (307)

Involvement of KEAP1/NRF2 pathway in non‐BRAF mutated squamous cell carcinoma of the thyroid

open access: yesThe Journal of Pathology, EarlyView.
Abstract Squamous cell carcinoma (SCC) of the thyroid is a rare tumor that is classified as an anaplastic thyroid cancer (ATC) due to its similar unresponsiveness to chemoradiotherapy and an outstandingly poor prognosis. Due to its rarity, current knowledge about this tumor is mostly based on single‐case reports.
Elin Schoultz   +13 more
wiley   +1 more source

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo   +2 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Iron-sulfur cluster 3 of beef heart succinate-ubiquinone oxidoreductase is a 3-iron cluster.

open access: hybrid, 1984
Brian A.C. Ackrell   +4 more
openalex   +1 more source

Comparative Dynamics Enables Discovery of Embedded Bacterial Ferredoxin Domains in Large Redox Enzymes

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Bacterial ferredoxins are small iron–sulfur binding proteins that function as soluble electron shuttles between redox enzymes in the cell. Their simple 2×(β–α–β) fold, central metabolic function, and ubiquity across all kingdoms of life have led to the proposal that ferredoxins were likely among the earliest proteins.
Jan A. Siess, Vikas Nanda
wiley   +1 more source

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