Results 21 to 30 of about 41,420 (299)

Targeting of the intracellular redox balance by metal complexes towards anticancer therapy

open access: yesFrontiers in Chemistry, 2022
The development of cancers is often linked to the alteration of essential redox processes, and therefore, oxidoreductases involved in such mechanisms can be considered as attractive molecular targets for the development of new therapeutic strategies.
María Isabel Murillo   +2 more
doaj   +1 more source

Inspired by Nature—Functional Analogues of Molybdenum and Tungsten-Dependent Oxidoreductases

open access: yesMolecules, 2022
Throughout the previous ten years many scientists took inspiration from natural molybdenum and tungsten-dependent oxidoreductases to build functional active site analogues.
Sebastian Pätsch   +4 more
doaj   +1 more source

Clinical evaluation of oxidative stress in patients with diabetes mellitus type II: Impact of acute exercise [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. Exercise is a well recognized model of oxidative stress and, also, an important tool in diabetes management. The aim of our study was to evaluate oxidative stress in patients with diabetes mellitus type 2 and to determine influence of ...
Kostić Nada   +6 more
doaj   +1 more source

Current Challenges for Biological Treatment of Pharmaceutical-Based Contaminants with Oxidoreductase Enzymes: Immobilization Processes, Real Aqueous Matrices and Hybrid Techniques

open access: yesBiomolecules, 2022
The worldwide access to pharmaceuticals and their continuous release into the environment have raised a serious global concern. Pharmaceuticals remain active even at low concentrations, therefore their occurrence in waterbodies may lead to successive ...
Helena Sá   +3 more
doaj   +1 more source

Laccases: Versatile Biocatalysts for the Synthesis of Heterocyclic Cores

open access: yesMolecules, 2021
Laccases are multicopper oxidases that have shown a great potential in various biotechnological and green chemistry processes mainly due to their high relative non-specific oxidation of phenols, arylamines and some inorganic metals, and their high redox ...
Ana Catarina Sousa   +2 more
doaj   +1 more source

Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain

open access: yesmBio, 2021
The nicotinamide cofactor specificity of enzymes plays a key role in regulating metabolic processes and attaining cellular homeostasis. Multiple studies have used enzyme engineering tools or a directed evolution approach to switch the cofactor preference
Madeleine Bouzon   +12 more
doaj   +1 more source

Fungal Treatment for the Valorization of Technical Soda Lignin

open access: yesJournal of Fungi, 2021
Technical lignins produced as a by-product in biorefinery processes represent a potential source of renewable carbon. In consideration of the possibilities of the industrial transformation of this substrate into various valuable bio-based molecules, the ...
Mariane Daou   +12 more
doaj   +1 more source

Characterization of a Dye-Decolorizing Peroxidase from Irpex lacteus Expressed in Escherichia coli: An Enzyme with Wide Substrate Specificity Able to Transform Lignosulfonates

open access: yesJournal of Fungi, 2021
A dye-decolorizing peroxidase (DyP) from Irpex lacteus was cloned and heterologously expressed as inclusion bodies in Escherichia coli. The protein was purified in one chromatographic step after its in vitro activation.
Laura Isabel de Eugenio   +6 more
doaj   +1 more source

Hypoxia Tolerance Declines with Age in the Absence of Methionine Sulfoxide Reductase (MSR) in Drosophila melanogaster

open access: yesAntioxidants, 2021
Unlike the mammalian brain, Drosophila melanogaster can tolerate several hours of hypoxia without any tissue injury by entering a protective coma known as spreading depression.
Nirthieca Suthakaran   +3 more
doaj   +1 more source

Thiol-disulfide oxidoreductases: assays, inhibitors, and metabolic roles

open access: yes, 2022
Thorpe, ColinDisulfide bonds are common post-translational modifications which serve to stabilize or impart function onto proteins. Although this product of oxidation between two cysteine thiols is relatively stable, disulfide bonds are able to undergo ...
Foster, Celia K.
core   +1 more source

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