Results 61 to 70 of about 91,003 (373)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Nanocatalysts Containing Direct Electron Transfer-Capable Oxidoreductases: Recent Advances and Applications

Catalysts, 2019
Direct electron transfer (DET)-capable oxidoreductases are enzymes that have the ability to transfer/receive electrons directly to/from solid surfaces or nanomaterials, bypassing the need for an additional electron mediator.
D. Ratautas, Marius Dagys
semanticscholar   +1 more source

Intracellular proteome expression during 4-n-nonylphenol biodegradation by the filamentous fungus Metarhizium robertsii [PDF]

, 2014
4-n-nonylphenol (4-n-NP) is an endocrine disrupting compound (EDC); pollutants that cause serious disturbances in the environment. This study shows the degradation pathway and initial proteome analysis in cultures of a fungus that actively degrades 4-n-
Dzitko , Katarzyna, Długoński, Jerzy, Różalska, Sylwia, Soboń, Adrian, Szewczyk, Rafał, Waidelich, Dietmar   +5 more
core   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex

mBio, 2017
Dengue virus (DENV) is the most common arboviral infection globally, infecting an estimated 390 million people each year. We employed a genome-wide clustered regularly interspaced short palindromic repeat (CRISPR) screen to identify host dependency ...
David L. Lin, Natalia A. Cherepanova, Leonia Bozzacco, Margaret R. MacDonald, Reid Gilmore, Andrew W. Tai   +5 more
doaj   +1 more source

Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. [PDF]

, 2015
The majority of those who drink excessive amounts of alcohol do not develop pancreatic disease. One overarching hypothesis is that alcohol abuse requires additional risk factors, either environmental or genetic, for disease to occur.
Lugea, Aurelia, Pandol, Stephen J, Waldron, Richard T   +2 more
core   +1 more source

Regulation of 3β-Hydroxysteroid Dehydrogenase/∆5-∆4 Isomerase: A Review [PDF]

, 2013
This review focuses on the expression and regulation of 3β-hydroxysteroi ddehydrogenase/Δ5-Δ4 isomerase (3β-HSD), with emphasis on the porcine version. 3β-HSD is often associated with steroidogenesis, but its function in the metabolism of both steroids ...
Abbaszade, Banner, Belanger, Beltowski, Benton, Berchtold, Bo Ekstrand, Brunius, Catalfo, Chapman, Chedrese, Chen, Chen, Cherradi, Clark, Coniglio, Conley, Conley, Conley, Cooke, Couet, Coulter, Cue, Davis, De Launoit, Doran, Doran, Dorgan, Dupont, Fink-Gremmels, Furster, Furster, Galarreta, Galia Zamaratskaia, Garrett, Garrett, Gingras, Gingras, Gromadzka-Ostrowska, Haider, Hassan, Havelock, Headon, Hierlihy, Hild-Petito, Hoog, Hu, Joernvall, Kallberg, Kaynard, Keeney, Keeney, Kershaw, Kiessling, Kostic, Kozlowska, Kumar, Labelle-Dumais, Labrie, LaVoie, Leers-Sucheta, Li, Liang, Lorence, Majdic, Martin, Martin Rasmussen, Mason, Mason, Matsunaga, Mcallister, Meadus, Mizrachi, Mode, Mullany, Nakajin, Nakamura, Naville, Nicolau-Solano, Papacleovoulou, Park, Payne, Payne, Payne, Pelletier, Penning, Picon, Rasmussen, Rasmussen, Rasmussen, Rasmussen, Saez, Samuels, Sasano, Sauer, Shapiro, Siiteri, Simard, Simard, Sirianni, Sordoillet, Stayrook, Sun, Suzuki, Takikawa, Takikawa, Tang, The, Tomankova, Tremblay, Val, Von Teichman, Walstra, Wang, Waxman, Waxman, Wong, Yuan, Zamaratskaia, Zamaratskaia, Zhao, Zinedine   +121 more
core   +2 more sources

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Screening of Microorganisms Producing Cold-Active Oxidoreductases to Be Applied in Enantioselective Alcohol Oxidation. An Antarctic Survey

Marine Drugs, 2011
Several microorganisms were isolated from soil/sediment samples of Antarctic Peninsula. The enrichment technique using (RS)-1-(phenyl)ethanol as a carbon source allowed us to isolate 232 psychrophile/psychrotroph microorganisms.
Leandro H. Andrade, Thaís P. Garcia, Vivian H. Pellizari, Lidiane S. Araújo, Edna Kagohara   +4 more
doaj   +1 more source