Results 81 to 90 of about 43,837 (307)

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

open access: yesAdvanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun   +9 more
wiley   +1 more source

State of enzyme systems of polymorphonuclear leukocytes by the gingival margin level correction

open access: yesКубанский научный медицинский вестник, 2015
The paper deals with the results of cytochemical studies of biologically active enzyme systems of neutrophilic granulocytes and their comparative analysis to assess the effectiveness of gingiva preparation and scalpel use for the correction of the ...
M. V. Goman   +2 more
doaj  

Endoplasmic reticulum (ER) Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition

open access: yesFrontiers in Oncology, 2014
Endoplasmic reticulum (ER) chaperones and oxidoreductases are abundant enzymes that mediate the production of fully folded secretory and transmembrane proteins. Resisting the Golgi and plasma membrane-directed bulk flow, ER chaperones and oxidoreductases
Thomas eSimmen, Tomas eGutierrez
doaj   +1 more source

PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species

open access: yesAdvanced Science, EarlyView.
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen   +19 more
wiley   +1 more source

Biocatalytic Isocitrate Production from Low‐Concentration Gaseous CO2 and Biobased 2‐Oxogultarate

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Biocatalytic isocitrate production from 2‐oxoglutarate and low‐concentration CO2 below 5% in the presence of NADPH and manganese ion was developed. Isocitrate dehydrogenase (IDH) from yeast (EC 1.1.1.42) is an enzyme that catalyzes the decarboxylating isocitrate into 2‐oxogurtarate and carbon dioxide and the reverse process of the introducing carbon ...
Masamichi Hino, Yutaka Amao
wiley   +1 more source

Soil Extracellular Enzymes from Brazilian Cerrado as Quality Bioindicators in Agricultural Areas in Goiás, Brazil

open access: yesFronteiras: Journal of Social, Technological and Environmental Science, 2016
The conversion of native Cerrado areas for the implementation of crops alters the physicochemical properties and biochemistry of soil. In this study we sought to understand the effect of seasonality and management used for planting sugarcane on the ...
Leciana de Menezes Sousa Zago   +5 more
doaj   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad   +9 more
wiley   +1 more source

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