Results 21 to 30 of about 38,531 (120)

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Duckweeds: Model organisms for research on plant sterols and steroids

Plant Biology, Volume 28, Issue 1, Page 18-30, January 2026.
Duckweeds (Lemnaceae), the fastest‐growing angiosperms and promising vegan protein source, offer a powerful model to address key questions in plant physiology. This article highlights their potential for dissecting the biosynthesis and function of phytosterols, sterol conjugates, brassinosteroids, and specialized steroidal metabolites, such as ...
J. Klein, K.‐J. Appenroth, K. S. Sree
wiley   +1 more source

Premature aging of red wines: a matter of fatty acid oxidation? A review on lipid‐derived molecular markers and their possible precursors

Journal of the Science of Food and Agriculture, Volume 105, Issue 15, Page 8315-8329, December 2025.
Abstract Premature aging of red wines (PremOx) is an emerging defect in red wines, related to the onset of cooked fruit, plum and dried figs nuances, as well as the loss of aging potential. This review is focussed on the contribute of lipid‐derived compounds, mainly originating from fatty acids oxidation, to this defect.
Ilaria Prezioso, Enrico Ottaviano, Giuseppe Corcione, Chiara Digiorgio, Gabriele Fioschi, Vito Michele Paradiso   +5 more
wiley   +1 more source

Transcriptomic and Targeted Metabolomic Analyses of Partially Resistant and Susceptible Pea Genotypes Reveal Differential Defense Responses During Their Interaction With Aphanomyces euteiches

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Aphanomyces root rot (ARR) incidence and prevalence are increasing throughout pea‐growing regions worldwide, highlighting the need for effective management strategies to safeguard yields. Understanding pea defense against ARR is essential for developing resistant cultivars.
Sijan Pandit, Hodan Halane, Stacy D. Singer, Nathaniel Zhin‐Loong Lim, Sangeeta Dhaubhadel, Ravinder Goyal, Wentao Zhang, Nora A. Foroud, Elizabeth Schultz, Syama Chatterton   +9 more
wiley   +1 more source

Opportunities When Chemistry Meets Biology in Catalysis and Synthesis

Transformative Chemistry, Volume 1, Issue 1, December 2025.
Biosynthesis and chemical synthesis possess complementary strengths and limitations. Integrating these two systems across multiple levels offers opportunities for molecular synthesis to become highly efficient, precise, versatile, and scalable in the future, while also ensuring environmental compatibility and resource renewability.
Xiao Xiao, Xinyi Ren, Baoguo Zhao, Xiaoguang Lei, Wen Liu, Kuiling Ding   +5 more
wiley   +1 more source

Winning by Losing: Exploiting Modified Plant Susceptibility Genes to Counteract Necrotrophic Fungal Pathogens

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5710-5727, December 2025.
ABSTRACT The infection of plants by pathogens is an intricate process in which genes from both the host and pathogen contribute to the infection process. Susceptibility (S) genes have been defined as plant genes that encode functions that are exploited by pathogens to invade and reproduce in host plants. Mutations in S‐genes therefore result in reduced
Yaohua You, Miguel Ramírez Gaona, Yuling Bai, Jan A. L. van Kan, Anne‐Marie A. Wolters   +4 more
wiley   +1 more source

Lactylation in cancer biology: Unlocking new avenues for research and therapy

Cancer Communications, Volume 45, Issue 11, Page 1367-1406, November 2025.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou, Zhenya Hong, Huimin Zeng, Changyi Zhang, Peng Zhang, Ding Ma, Zhiqiang Han   +6 more
wiley   +1 more source

Anaerobic Limonene Metabolism in a Methanogenic Enrichment Involves a Glycine Radical Enzyme

Environmental Microbiology, Volume 27, Issue 11, November 2025.
A methanogenic enrichment culture on the natural monoterpene limonene is characterised by a novel glycine radical enzyme for anaerobic hydrocarbon activation, the presence of a microbial loop for necromass utilisation and the presence of a predator of Bacteria and Archaea. ABSTRACT Limonene is a natural monoterpene omnipresent in human environments. It
Almud Lonsing, Gerrit Alexander Martens, Anastasia Resteu, Jana Kizina, Isabella Wilkie, Alexandra Bahr, Jens Harder   +6 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

Ru‐Catalyzed Asymmetric Transfer Hydrogenation of α‐iminophosphonates: A Novel Synthetic Approach for Valuable Chiral α‐Aminophosphonates

Chemistry – A European Journal, Volume 31, Issue 55, October 1, 2025.
This study reports the first Ru‐catalyzed ATH of α‐iminophosphonates, enabling the efficient synthesis of chiral α‐aminophosphonates. Both acyclic and cyclic substrates are converted in high yields (up to 97%) with excellent enantioselectivities (up to >99:1), offering a practical alternative to conventional AH for accessing phosphorus‐containing ...
Pierre Plouard, Laura Borrel, Pierre‐Olivier Butin, Paul Muller, Rémi Cherpitel, Séverine Loiseau, Ludovic Clarion, David Virieux, Tahar Ayad   +8 more
wiley   +1 more source