Results 181 to 190 of about 60,467 (293)

Protein-induced membrane strain drives supercomplex formation. [PDF]

Elife
Pöverlein MC, Jussupow A, Kim H, Kaila VRI.   +3 more
europepmc   +1 more source

Absolute Quantification of Brain Deuterium Metabolic Imaging in Healthy Volunteers and Glioblastoma Patients at 7T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose We present a method for absolute quantification of deuterated metabolites in vivo at 7T. We describe acquisition protocols and an analysis pipeline compatible with 7T Terra MRIs. We apply them using a 2H/1H receive array in healthy volunteers and glioblastoma patients.
Jabrane Karkouri, Masha Novoselova, Sarah Miller, Minghao Zhang, Alexandra Constantinou, Carina Graf, Özlem Ipek, Daniel Atkinson, Brandon Tramm, Scott Schillak, Richard Mair, Kevin Brindle, Christopher T. Rodgers   +12 more
wiley   +1 more source

Pim1 Serves as a Therapeutic Target for Inflammatory Arthritis via Mitochondrial Metabolism and Th17 Cell Differentiation. [PDF]

Research (Wash D C)
Su Z, Zeng Y, Li Q, Li J, Zheng G, Zhang W, Xiao Z, Chen Z, Lin Y, Liu Z, Wu Y, Lin J, Yu W, Xie Z.   +13 more
europepmc   +1 more source

Acute Inhalation Exposure to Ultrafine Carbon Black Alters Mitochondrial Substrate Utilization in the Heart

Environmental Toxicology, EarlyView.
ABSTRACT A majority of deaths associated with air pollution are attributed to cardiovascular and heart diseases. Carbon black that represents the carbon core of particulate matter, a major component of air pollution, has been shown to result in cardiac mitochondrial dysfunction.
William E. Mullen, Jackson E. Stewart, Rahatul Islam, Salik Hussain, Dharendra Thapa   +4 more
wiley   +1 more source

Quantifying variability of mitochondrial markers in m3243A > G myopathy. [PDF]

Sci Rep
Bernardino Gomes TM, Childs JB, Di Leo V, Warren C, Hudson G, Turnbull DM, Lawless C, Vincent AE.   +7 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Immune Cell Mitochondrial Phenotypes Are Largely Preserved in Mitochondrial Diseases and Do Not Reflect Disease Severity. [PDF]

Neurol Genet
Liu CC, Kurade M, Monzel AS, Kelly C, Juster RP, Trumpff C, Hirano M, Picard M.   +7 more
europepmc   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Hypoxia leads to reduced mito-nuclear gene expression and increased mtDNA transcriptional pausing in human cells. [PDF]

Commun Biol
Shtolz N, Dadon S, Mishmar D.
europepmc   +1 more source