Results 231 to 240 of about 51,375 (281)

PDHA1 Hyperactivation Orchestrates Metabolic Reprogramming Promoting Endothelial Senescence. [PDF]

Research (Wash D C)
Zhong WJ, Yang NS, Zhang CY, Liu YB, Jin L, Ou AJ, Chen H, Li J, Zhou Y, He BM, Duan JX.   +10 more
europepmc   +1 more source

Dynamic Metabolic States in TNBC: Orchestrating Spatiotemporal Adaptation and Therapy. [PDF]

Oncol Res
Wang Y, You H, Gao J, Zhang F, Ning X, Yang X, Qian Z, Jiang Y, Liu L, Wu D, Gu Y, Chen D, Zhang Y.   +12 more
europepmc   +1 more source

Mitochondria in health and disease: cellular powerhouses, signaling centers, and drivers of dysfunction. [PDF]

Front Cell Dev Biol
Akinkunmi OA, Araba FF, Chukwudebelu JA, Adenle VA, Odeyemi AA, Akhigbe TM, Akhigbe RE.   +6 more
europepmc   +1 more source

Mapping metabolic reprogramming dynamics across pancreatic neuroendocrine tumor cell differentiation at single-cell transcriptomic resolution. [PDF]

Front Genet
Yu P, Xiao J.
europepmc   +1 more source

In vivo and in organello assessment of OXPHOS activities

Methods, 2002
Mitochondrial OXPHOS defects are responsible for a large group of human diseases and have been associated with degenerative disorders and aging. The accurate in vivo and in organello biochemical assessment of the OXPHOS system is necessary for the diagnosis and investigation of such conditions.
Antoni Barrientos
exaly   +4 more sources

Coordinating mitochondrial translation with assembly of the OXPHOS complexes [PDF]

Human Molecular Genetics
Abstract The mitochondrial oxidative phosphorylation (OXPHOS) system produces the majority of energy required by cells. Given the mitochondrion’s endosymbiotic origin, the OXPHOS machinery is still under dual genetic control where most OXPHOS subunits are encoded by the nuclear DNA and imported into mitochondria, while a small subset is ...
Peter Rehling
exaly   +6 more sources

Genetic defects in the oxidative phosphorylation (OXPHOS) system

Expert Review of Molecular Diagnostics, 2004
The oxidative phosphorylation (OXPHOS) system consists of five multiprotein complexes and two mobile electron carriers embedded in the lipid bilayer of the mitochondrial inner membrane. With the exception of complex II and the mobile carriers, the other parts of the OXPHOS system are under dual genetic control.
Lambert P van den Heuvel
exaly   +5 more sources

Targeting Mitochondrial OXPHOS and Their Regulatory Signals in Prostate Cancers

International Journal of Molecular Sciences, 2021
Increasing evidence suggests that tumor development requires not only oncogene/tumor suppressor mutations to drive the growth, survival, and metastasis but also metabolic adaptations to meet the increasing energy demand for rapid cellular expansion and ...
Ching-yu Lin, Ching Yu Lin, Chia-Lin Chen   +2 more
exaly   +3 more sources