Results 261 to 270 of about 60,467 (293)

Metabolism of tumor infiltrating T cells. [PDF]

Front Immunol
Ertl HC.
europepmc   +1 more source

Impaired mitochondrial ketone body oxidation in insulin resistant states. [PDF]

EBioMedicine
Zweck E, Piel S, Schmidt JW, Scheiber D, Schön M, Kahl S, Burkart V, Dewidar B, Remus R, Chadt A, Al-Hasani H, Mastrototaro L, Aubin H, Boeken U, Lichtenberg A, Distler J, Polzin A, Kelm M, Westenfeld R, Wagner R, Schrauwen P, Szendroedi J, Roden M, Granata C.   +23 more
europepmc   +1 more source

Impact of dietary essential fatty acids on phospholipid composition and mitochondrial function in aged mares. [PDF]

Sci Rep
Fresa K, Catandi GD, Gonzalez-Castro R, Omar A, Whitcomb LA, Cheng MH, Chen TW, Carnevale EM, Chicco AJ.   +8 more
europepmc   +1 more source

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Mitochondrial OXPHOS complex assembly lines

Nature Cell Biology, 2018
Mitochondria are critical for cellular energy generation and house oxidative phosphorylation (OXPHOS) complexes, which are under dual genetic control. A study finds that transcript translation and complex assembly are partitioned, and OXPHOS complexes III, IV and V are built at spatially defined regions of the mitochondrial inner membrane.
Luke E, Formosa, Michael T, Ryan
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Immortalizing switch to OXPHOS

Nature Reviews Molecular Cell Biology, 2020
The switch from glycolytic metabolism to OXPHOS functions as a driver of cell immortalization during tumorigenesis in the fly brain.
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OXPHOS inhibitors, metabolism and targeted therapies in cancer

Biochemical Pharmacology, 2023
More and more studies highlight the complex metabolic characteristics and plasticity of cancer cells. To address these specificities and explore the associated vulnerabilities, new metabolism-targeting therapeutic strategies are being developed. It is more and more accepted that cancer cells do not produce their energy only from aerobic glycolysis, as ...
Cadassou, Octavia, Jordheim, Lars Petter
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OXPHOS Supercomplexes

Annals of the New York Academy of Sciences, 2006
Abstract:  Recent biochemical evidence has indicated the existence of respiratory supercomplexes as well as ATP synthase oligomers in the inner mitochondrial membrane of different eukaryotes. We have studied the organization of the respiratory chain of a wild‐type strain and of two long‐lived mutants of the filamentous fungus Podospora anserina.
Frank, Krause, Christian Q, Scheckhuber, Alexandra, Werner, Sascha, Rexroth, Nicole H, Reifschneider, Norbert A, Dencher, Heinz D, Osiewacz   +6 more
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Therapeutic Options in OXPHOS Disorders

2007
No curative treatment of OXPHOS disorders is currently available, despite great progress in our understanding of the molecular bases of these diseases. We review available and experimental therapeutic approaches that fall into the following categories:
Rob C. A. Sengers, J. M. Frans Trijbels, Carolien C. A. Boelen, Eva Morava, Jan A. M. Smeitink   +4 more
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