Results 111 to 120 of about 27,463 (211)
Drug Design, Development and Therapy, 2018 Meilin Liu, Xiaolong Chen, Henan Liu, Yu Di Department of Ophthalmology, Shengjing Affiliated Hospital, China Medical University, Shenyang, Liaoning, People’s Republic of China Aim: The aim of the study was to investigate the signal transduction ...
Liu ML, Chen XL, Liu HN, Di Y
doaj
Early Depletion of Neutrophils Reduces Retinal Inflammation and Neovascularization in Mice with Oxygen-Induced Retinopathy. [PDF]
Int J Mol Sci, 2023 Deliyanti D +5 more
europepmc +1 more source
Oxygen-induced retinopathy in newborn kittens. A model for ischemic vasoproliferative retinopathy.
Investigative ophthalmology & visual science, 1987 Fourteen kittens were reared in 80% oxygen for 65-72 hr, after which they were returned to room air. At that time, funduscopic examination of all the kittens showed complete obliteration of the retinal vasculature and even optic disc vessels. In the following 18-21 days, florid preretinal new vessels were found growing into the vitreous from the ...
I, Kremer +4 more
openaire +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.Diabetes mellitus causes significant damage to the male reproductive system. Sirt1/Nrf2/HO‐1 signaling pathway acts as a line of defense against ROS in reproductive organs. In STZ‐induced diabetic rats, the proapoptotic Bax protein expression was found to be elevated, whereas the antiapoptotic Bcl‐2 protein expression was reduced.
Edanur Güler Ekmen +3 more
wiley +1 more source
Proteomics Analysis of R-Ras Deficiency in Oxygen Induced Retinopathy. [PDF]
Int J Mol Sci, 2023 Vähätupa M +5 more
europepmc +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.Biogenic silver nanoparticles exhibit antidiabetic potential by improving glycemic control, enhancing insulin sensitivity, and preserving pancreatic β‐cell function. They act through antioxidant and anti‐inflammatory mechanisms, modulating ROS, NF‐κB, and PI3K/Akt pathways, while providing multi‐organ protection, highlighting their promise as ...
Nourhane A. Darwich +2 more
wiley +1 more source
AggregateRetinal neovascularization (RNV) drives dual pathological cascades: structural destruction characterized by intraretinal/vitreous hemorrhages and tractional retinal detachment, alongside functional decline marked by progressive neurodegeneration and ...
Mengdie Li +15 more
doaj +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, Volume 2, Issue 2, Page 309-342, June 2026.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Neuroprotective Effects of Human Adipose-Derived Mesenchymal Stem Cells in Oxygen-Induced Retinopathy. [PDF]
Cell Transplant, 2023 Xin J, Zhou L, Zhang L, Guo K, Yang D.
europepmc +1 more source