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Biocompatibility Studies with Perfluorochemical Oxygen Carriers
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1992The effects of injecting either a novel perfluorodecalin (FDC)-based emulsion or various perfluorochemical (PFC) oils on liver cytochromes P-450 (P-450) and aryl esterase (LAE) enzymes in male rats have been studied. Mean P-450 concentration increased (P less than 0.05) following injection of the novel emulsion or FDC.
K C, Lowe, F H, Armstrong
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1985
The authors wish to dedicate this article to the memory of Professor Eraldo Antonini, who died of an incurable illness on 19 March 1983. It was Professor Antonini who introduced the authors to the study of oxygen-carrying proteins and inspired their scientific activity.
Maurizio Brunori +2 more
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The authors wish to dedicate this article to the memory of Professor Eraldo Antonini, who died of an incurable illness on 19 March 1983. It was Professor Antonini who introduced the authors to the study of oxygen-carrying proteins and inspired their scientific activity.
Maurizio Brunori +2 more
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Critical reviews in therapeutic drug carrier systems, 1987
During the last decade, construction of artificial carriers of oxygen for transfusion purposes has evolved in three main directions, which can be reviewed as follows. The first approach consists of modifying hemoglobin (Hb), the natural oxygen carrier, in order to lower its oxygen affinity and increase its intravascular persistence. To achieve this aim,
E, Dellacherie +3 more
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During the last decade, construction of artificial carriers of oxygen for transfusion purposes has evolved in three main directions, which can be reviewed as follows. The first approach consists of modifying hemoglobin (Hb), the natural oxygen carrier, in order to lower its oxygen affinity and increase its intravascular persistence. To achieve this aim,
E, Dellacherie +3 more
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Oxygen Transport to Renal Tissue: Effect of Oxygen Carriers
1987The isolated perfused rat kidney introduced by Weiss and colleagues in 1959 has become a commonly used tool in the field of renal physiology and pharmacology (Weiss, Passow and Rothstein, 1959; Little and Cohen, 1974; Ross, 1978; Maack, 1986). In view of technical complications such as blood clotting and the release of vasoactive factors most authors ...
G, Gronow +4 more
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1986
Opening Session.- Homage to Rene Lontie.- Hemerythrins.- Structure, function and oxidation levels of hemerythrin.- Structure and Function of Invertebrate Hemoglobins.- The dissociation of the extracellular hemoglobin of Lumbricus terrestris: A model of its subunit structure.- Subunit structure of earthworm erythrocruorin.- Characterization of trimeric ...
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Opening Session.- Homage to Rene Lontie.- Hemerythrins.- Structure, function and oxidation levels of hemerythrin.- Structure and Function of Invertebrate Hemoglobins.- The dissociation of the extracellular hemoglobin of Lumbricus terrestris: A model of its subunit structure.- Subunit structure of earthworm erythrocruorin.- Characterization of trimeric ...
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Baillière's Clinical Anaesthesiology, 1988
Summary At present there are two credible forms of artificial oxygen carrier for intravascular use. Polymerized tensed haemoglobin solutions have very similar characteristics to red cells but are still difficult to produce in nontoxic forms. They have the advantage that they can accept a full load of oxygen by exposure to normal alveolar air.
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Summary At present there are two credible forms of artificial oxygen carrier for intravascular use. Polymerized tensed haemoglobin solutions have very similar characteristics to red cells but are still difficult to produce in nontoxic forms. They have the advantage that they can accept a full load of oxygen by exposure to normal alveolar air.
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A New Oxygen Carrier for Therapeutic Applications
Drug Testing and AnalysisABSTRACTThe natural extracellular hemoglobin of the lugworm Arenicola marina (AmHb) has many interesting characteristics: It carries 40 times more oxygen than human hemoglobin; has anti‐inflammatory, antibacterial, and antioxidant properties; and is 250 times smaller than a red blood cell. It is nontoxic and nonimmunogenic.
Benoit Barrou +2 more
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An Overview on Oxygen Carriers in Cancer Therapy
Artificial Cells, Blood Substitutes, and Biotechnology, 1995Solid tumors are aberrant tissues composed of stroma and malignant cells. Amongst the properties which distinguish normal tissues from solid tumors are physiological characteristics related to the disregulated proliferation of the neoplastic and normal cells that comprise the tumor mass. Although signals for vascular growth are present in solid tumors,
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