Results 1 to 10 of about 216,047 (380)
Haematologica, 2015 Heme oxygenase-1 is critical for iron recycling during red blood cell turnover, whereas its impact on steady-state erythropoiesis and red blood cell lifespan is not known. We show here that in 8- to 14-week old mice, heme oxygenase-1 deficiency adversely
Stuart T. Fraser +13 more
doaj +2 more sources
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim +6 more
core +2 more sources
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1968 R Tenhunen, Harvey S. Marver, R. Schmid
openalex +2 more sources
Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury. [PDF]
SAGE Open MedObjective: Ischemia-reperfusion injury exacerbates myocardial damage and affects the prognosis of patients with ST-elevation myocardial infarction. This study investigates the potential cytoprotective effects of hemin in an in vitro cardiomyocyte model ...
Wang Z, Liu W.
europepmc +2 more sources
Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions
Biomolecules, 2021 Heme-oxygenase is the enzyme responsible for degradation of endogenous iron protoporphyirin heme; it catalyzes the reaction’s rate-limiting step, resulting in the release of carbon monoxide (CO), ferrous ions, and biliverdin (BV), which is successively ...
Valeria Consoli +3 more
semanticscholar +1 more source
Structure and mutation of deoxypodophyllotoxin synthase (DPS) from Podophyllum hexandrum
Frontiers in Catalysis, 2023 Deoxypodophyllotoxin synthase (DPS) is a 2-oxoglutarate (2-OG) dependent non-heme iron (II) dioxygenase that catalyzes the stereoselective ring-closing carbon-carbon bond formation of deoxypodophyllotoxin from the aryllignan (−)-yatein ...
Zoe Ingold +3 more
doaj +1 more source
Microorganisms, 2022 The widespread use of plastics has led to their increasing presence in the environment and subsequent pollution. Some microorganisms degrade plastics in natural ecosystems and the associated metabolic pathways can be studied to understand the degradation
Anutthaman Parthasarathy +6 more
doaj +1 more source
The Diverse Roles of Heme Oxygenase-1 in Tumor Progression
Frontiers in Immunology, 2021 Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in response to a variety of stimuli to degrade heme, which generates the biologically active catabolites carbon monoxide (CO), biliverdin and ferrous iron (Fe2+).
Kim Ngan Luu Hoang +2 more
semanticscholar +1 more source