Results 11 to 20 of about 219,353 (382)
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Bugg, Tim +6 more
core +2 more sources
Haematologica, 2015 Heme oxygenase-1 is critical for iron recycling during red blood cell turnover, whereas its impact on steady-state erythropoiesis and red blood cell lifespan is not known. We show here that in 8- to 14-week old mice, heme oxygenase-1 deficiency adversely
Stuart T. Fraser +13 more
doaj +2 more sources
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1968 R Tenhunen, Harvey S. Marver, R. Schmid
openalex +2 more sources
Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions
Biomolecules, 2021 Heme-oxygenase is the enzyme responsible for degradation of endogenous iron protoporphyirin heme; it catalyzes the reaction’s rate-limiting step, resulting in the release of carbon monoxide (CO), ferrous ions, and biliverdin (BV), which is successively ...
Valeria Consoli +3 more
semanticscholar +1 more source
The Diverse Roles of Heme Oxygenase-1 in Tumor Progression
Frontiers in Immunology, 2021 Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in response to a variety of stimuli to degrade heme, which generates the biologically active catabolites carbon monoxide (CO), biliverdin and ferrous iron (Fe2+).
Kim Ngan Luu Hoang +2 more
semanticscholar +1 more source
Applied Microbiology and Biotechnology, 2018 Natural rubber (NR), poly(cis-1,4-isoprene), is used in an industrial scale for more than 100 years. Most of the NR-derived materials are released to the environment as waste or by abrasion of small particles from our tires. Furthermore, compounds with isoprene units in their molecular structures are part of many biomolecules such as terpenoids and ...
Dieter Jendrossek, Jakob Birke
openaire +2 more sources
Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice [PDF]
, 2017 Hepcidin, a phase II reactant secreted by hepatocytes, regulates cellular iron levels by increasing internalization of ferroportin-a transmembrane protein facilitating egress of cellular iron.
Arefiev, Yevgeniy +12 more
core +2 more sources
Custom tuning of Rieske oxygenase reactivity
Nature Communications, 2023 Rieske oxygenases use a Rieske-type [2Fe-2S] cluster and a mononuclear iron center to initiate a range of chemical transformations. However, few details exist regarding how this catalytic scaffold can be predictively tuned to catalyze divergent reactions.
Jiayi Tian +5 more
doaj +1 more source